10.46243/jstj.2017.v2.i6.38 registered
New Validated RP-HPLC Method For The Estimation of Ertapenem In Pharmaceutical Formulation
Resolves to https://www.jst.org.in/index.php/pub/article/view/38
Held by Longman Publishers (India) · prefix 10.46243 live · DOI address https://doi.org/10.46243/jstj.2017.v2.i6.38
Registered 29 Sep 2026 via crossref · record version 2 · last change 29 Sep 2026, 11:59 PM · record sha256 7b609b9483cbb863…
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JournalArticle — an article in a journal · Digital · Visual · en
New Validated RP-HPLC Method For The Estimation of Ertapenem In Pharmaceutical Formulation (PrincipalTitle)
Published 2017-12-10
Part of Journal of Science & Technology · ISSN 2456-5660 · volume 02 · issue 06 · pages 06–12
Agents
- M. Sivanadh (author)
- Longman Publishers (publisher)
Identifiers DOI 10.46243/jstj.2017.v2.i6.38
Abstract
A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of Ertapenem in Bulk and Pharmaceutical tablet Formulation. Isocratic elution at a flow rate of 1.5 ml/min was employed on symmetry Shimadzu LC-20 ATVP Kromasil C-18 Column at ambient temperature. The mobile phase consisted of 0.01M Potassium di-hydrogen phosphate : Water : Acetonitrile (25:50:25 v/v) . The UV detection wavelength was 295nm and 20μl sample was injected. The run time for Ertapenem is 15 min. The Percentage assay of Ertapenem in formulation was found to be 100.01%. The amount of drug present in the human sample was found to be 0.287 mg/ ml The limit of detection for Ertapenem was found to be 20μg/ml and the limit of quantification was found to be 50μg/ml.The method was validated as per the ICH guidelines. The method was successfully applied for routine quality control analysis of pharmaceutical formulation. The HPLC method can be successfully applied for the routine quality control analysis of Ertapenem formulations.
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Each element by the standard's name (Annex B: reference elements, then administrative) and the Handbook's (in grey), read off the record above.
| Element | Value | In the record |
|---|---|---|
| DOI Name DOI name | 10.46243/jstj.2017.v2.i6.38 | doi |
| Referent Type referentType | Creation | referent |
| Referent Sub-Type referentSubType | JournalArticle — an article in a journal | type |
| Referent Name(s) referentName(s) | New Validated RP-HPLC Method For The Estimation of Ertapenem In Pharmaceutical Formulation (PrincipalTitle, en) | titles |
| Basic Metadata basicMetadata | author: M. Sivanadh publisher: Longman Publishers published: 2017-12-10 part of: Journal of Science & Technology · ISSN 2456-5660 · vol. 02 · no. 06 · pp. 06–12 language: en form: Digital · Visual · Language | agents, dates, container, language, structural_type, modes, characters |
| Referent Identifier(s) alternateIdentifier(s) | none besides the DOI | identifiers, relations (IsSameAs) |
| Registration Authority registrationAuthorityCode | Crossref — issued by Crossref (member 25296); held here as a copy | record.source_agency (our code, ra_doi_name, for names issued here once appointed) |
| Created Date issueDate | 2026-09-07 | record.registered (when the DOI name was first registered) |
| relatedIdentifiers | none needed — the descriptive metadata is in this record | container, relations (only where the descriptive metadata lives at another identifier) |
complete Every System Metadata element is here, with the basic metadata a journal article needs.
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Every change to this DOI, in order, as it was recorded. Entries are only ever added, never changed or removed.
| # | When | What | By | Changes |
|---|---|---|---|---|
| 1 | 29 Sep 2026, 10:00 PM | register registered at Crossref; record read from api.crossref.org | Administrator (admin) | 86 fields set · sha256 8844f983b721… |
| 2 | 29 Sep 2026, 11:59 PM | update record re-read from api.crossref.org | Administrator (admin) | container.titles.0.value: |
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