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                "abstract": {
                    "value": "A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of Ertapenem in Bulk and Pharmaceutical tablet Formulation. Isocratic elution at a flow rate of 1.5 ml/min was employed on symmetry Shimadzu LC-20 ATVP Kromasil C-18 Column at ambient temperature. The mobile phase consisted of 0.01M Potassium di-hydrogen phosphate : Water : Acetonitrile (25:50:25 v/v) . The UV detection wavelength was 295nm and 20μl sample was injected. The run time for Ertapenem is 15 min. The Percentage assay of Ertapenem in formulation was found to be 100.01%. The amount of drug present in the human sample was found to be 0.287 mg/ ml The limit of detection for Ertapenem was found to be 20μg/ml and the limit of quantification was found to be 50μg/ml.The method was validated as per the ICH guidelines. The method was successfully applied for routine quality control analysis of pharmaceutical formulation. The HPLC method can be successfully applied for the routine quality control analysis of Ertapenem formulations.",
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                        "key": "ref1",
                        "doi": "10.1517/14656566.9.1.23",
                        "unstructured": "The MerckIndex, 13thedition, Merckandcompany, INC, White House station, NJ, 2001, 653. Shah PM, Issaca RD. Ertapenem, the fi rst of a new group of carbapenem. J Antimicrob Chemother. 2003; 52: 538-42. Nicolau DP. Carbapenems: a potent class of antibiotics. Expert Opin Pharmacother. 2008; 9: 23-37. Nix DE, Majumdar AK, DiNubile MJ. Pharmacokinetics and pharmacodynamics of Ertapenem: an overview for clinicians. J Antimicrob Chemother. 2004; 53 Suppl 2:23-8"
                    },
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                        "key": "ref2",
                        "doi": "10.1128/aac.45.6.1915-1918.2001",
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                        "key": "ref3",
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                    },
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                        "key": "ref4",
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                        "key": "ref5",
                        "doi": "10.1093/jac/dkg404",
                        "unstructured": "Shah PM, Isaacs RD. Ertapenem, the first of a new group of carbapenems. J Antimicrob Chemother. 2003;52:538–542"
                    },
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                        "doi": "10.1093/jac/dkg375",
                        "unstructured": "Livermore DM, Sefton AM, Scott GM. Properties and potential of ertapenem. J Antimicrob Chemother. 2003;52:331–344"
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                        "key": "ref7",
                        "doi": "10.1093/jac/dkh204",
                        "unstructured": "Wexler HM. In vitro activity of ertapenem: review of recent studies. J Antimicrob Chemother.2004;53:23-28"
                    },
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                        "doi": "10.1016/s0924-8579(02)00129-2",
                        "unstructured": "Hilliard NJ, Johnson CN, Armstrong SH, Quarles S, Waites KB. In vitro activity of ertapenem(MK-0826) against multi-drug resistant Streptococcus pneumoniae compared with 13 other antimicrobials. Int J Antimicrob Agent. 2002; 20:136–140"
                    },
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                        "doi": "10.4061/2011/232505",
                        "unstructured": "M.V.Basaveswara Rao,1 A.V.D.Nagendrakumar,2SushantaMaiti,3and N. Chandrasekhar1 Validated RP-HPLC Method for the Estimation of Stavudine in Formulation and Serum Research Journal of Pharmaceutical, Biological and Chemical Sciences; 2011, 2(3) :872-879"
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                        "key": "ref10",
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                        "unstructured": "L.Venkateswara Rao, G.Ramu, M. Sravan Kumar and C.Rambabu* Reverse Phase HPLC and Visible Spectrophotometric Methods for the Determination of Meropenem in Pure and Pharmaceutical Dosage Form International Journal of PharmTech Research Vol.4, No.3, pp 957-962, July-Sept 2012"
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