Cite this DOI

M. Sivanadh (2017). New Validated RP-HPLC Method For The Estimation of Ertapenem In Pharmaceutical Formulation. *Journal of Science & Technology*, *02*(06), 06–12. https://doi.org/10.46243/jstj.2017.v2.i6.38

@article{msivanadh2017validated,
  author    = {M. Sivanadh},
  title     = {{New Validated RP-HPLC Method For The Estimation of Ertapenem In Pharmaceutical Formulation}},
  journal   = {Journal of Science \& Technology},
  year      = {2017},
  month     = {dec},
  volume    = {02},
  number    = {06},
  pages     = {06--12},
  publisher = {Longman Publishers},
  issn      = {2456-5660},
  doi       = {10.46243/jstj.2017.v2.i6.38},
  url       = {https://doi.org/10.46243/jstj.2017.v2.i6.38},
  language  = {en},
  abstract  = {A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of Ertapenem in Bulk and Pharmaceutical tablet Formulation. Isocratic elution at a flow rate of 1.5 ml/min was employed on symmetry Shimadzu LC-20 ATVP Kromasil C-18 Column at ambient temperature. The mobile phase consisted of 0.01M Potassium di-hydrogen phosphate : Water : Acetonitrile (25:50:25 v/v) . The UV detection wavelength was 295nm and 20μl sample was injected. The run time for Ertapenem is 15 min. The Percentage assay of Ertapenem in formulation was found to be 100.01\%. The amount of drug present in the human sample was found to be 0.287 mg/ ml The limit of detection for Ertapenem was found to be 20μg/ml and the limit of quantification was found to be 50μg/ml.The method was validated as per the ICH guidelines. The method was successfully applied for routine quality control analysis of pharmaceutical formulation. The HPLC method can be successfully applied for the routine quality control analysis of Ertapenem formulations.}
}

TY  - JOUR
TI  - New Validated RP-HPLC Method For The Estimation of Ertapenem In Pharmaceutical Formulation
AU  - M. Sivanadh
JO  - Journal of Science & Technology
PY  - 2017
DA  - 2017/12/10/
VL  - 02
IS  - 06
SP  - 06
EP  - 12
PB  - Longman Publishers
SN  - 2456-5660
LA  - en
AB  - A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of Ertapenem in Bulk and Pharmaceutical tablet Formulation. Isocratic elution at a flow rate of 1.5 ml/min was employed on symmetry Shimadzu LC-20 ATVP Kromasil C-18 Column at ambient temperature. The mobile phase consisted of 0.01M Potassium di-hydrogen phosphate : Water : Acetonitrile (25:50:25 v/v) . The UV detection wavelength was 295nm and 20μl sample was injected. The run time for Ertapenem is 15 min. The Percentage assay of Ertapenem in formulation was found to be 100.01%. The amount of drug present in the human sample was found to be 0.287 mg/ ml The limit of detection for Ertapenem was found to be 20μg/ml and the limit of quantification was found to be 50μg/ml.The method was validated as per the ICH guidelines. The method was successfully applied for routine quality control analysis of pharmaceutical formulation. The HPLC method can be successfully applied for the routine quality control analysis of Ertapenem formulations.
DO  - 10.46243/jstj.2017.v2.i6.38
UR  - https://doi.org/10.46243/jstj.2017.v2.i6.38
ER  -

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    "DOI": "10.46243/jstj.2017.v2.i6.38",
    "URL": "https://doi.org/10.46243/jstj.2017.v2.i6.38",
    "title": "New Validated RP-HPLC Method For The Estimation of Ertapenem In Pharmaceutical Formulation",
    "source": "Smart Scholars DOI Registry",
    "container-title": "Journal of Science & Technology",
    "author": [
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                12,
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    "volume": "02",
    "issue": "06",
    "page": "06-12",
    "publisher": "Longman Publishers",
    "language": "en",
    "abstract": "A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of Ertapenem in Bulk and Pharmaceutical tablet Formulation. Isocratic elution at a flow rate of 1.5 ml/min was employed on symmetry Shimadzu LC-20 ATVP Kromasil C-18 Column at ambient temperature. The mobile phase consisted of 0.01M Potassium di-hydrogen phosphate : Water : Acetonitrile (25:50:25 v/v) . The UV detection wavelength was 295nm and 20μl sample was injected. The run time for Ertapenem is 15 min. The Percentage assay of Ertapenem in formulation was found to be 100.01%. The amount of drug present in the human sample was found to be 0.287 mg/ ml The limit of detection for Ertapenem was found to be 20μg/ml and the limit of quantification was found to be 50μg/ml.The method was validated as per the ICH guidelines. The method was successfully applied for routine quality control analysis of pharmaceutical formulation. The HPLC method can be successfully applied for the routine quality control analysis of Ertapenem formulations.",
    "ISSN": "2456-5660"
}

From the record as registered (version 2) — the record and its history. Programs: https://registry.smartscholars.in/api.php?action=cite&doi=10.46243%2Fjstj.2017.v2.i6.38 gives all four in one JSON answer.