10.46243/jst.2025.v10.i6.pp37-47 registered
AntimicrobialResistanceProfileofDifferentClinicalIsolatesagainstThird-GenerationCephalosporins
Resolves to https://www.jst.org.in/index.php/pub/article/view/1373
Held by Longman Publishers (India) · prefix 10.46243 live · DOI address https://doi.org/10.46243/jst.2025.v10.i6.pp37-47
Registered 29 Sep 2026 via crossref · record version 2 · last change 29 Sep 2026, 11:59 PM · record sha256 9ffa5b75fdf54df2…
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JournalArticle — an article in a journal · Digital · Visual · en
AntimicrobialResistanceProfileofDifferentClinicalIsolatesagainstThird-GenerationCephalosporins (PrincipalTitle)
Published 2025-06-20
Part of Journal of Science & Technology · ISSN 2456-5660 · volume 10 · issue 06 · pages 37–47
Agents
- DRBVRAMANA (author)
- S.K.RUBINA (author)
- DRMSANTOSHRAJA (author)
- AHEMANTH (author)
- S.AFREENJEHA (author)
- Longman Publishers (publisher)
Identifiers DOI 10.46243/jst.2025.v10.i6.pp37-47
Abstract
death because they increase the likelihood of harmful treatment. Antimicrobial resistance statistics therefore aid in determining optimal patient care. Consequently, the purpose of this research was to examine the antimicrobial resistance pattern of third-generation cephalosporin medications at Jimma University Specialized Teaching Hospital. Methods. From April to August 2016, researchers at Jimma University Specialized Hospital (JUSH) performed a prospective cross-sectional study in a hospital setting. Patients in hospitals had their urine, sputum, wound swabs, and feces collected for clinical purposes. Following this, the usual microbiological procedures were followed in order to isolate and identify the bacterial species. Using the Kirby-Bauer disc diffusion technique, we tested the susceptibility of different microorganisms to antimicrobials. Final product. Out of a total of 248 bacterial isolates, 154 (62.1%) were found in male patients and 94 (37.0%) were found in female patients. Specimens were most often found to include Escherichia coli (25.4% of the total) and Staphylococcus aureus (19.0%). Approximately 56.5% of the total bacterial isolates (140) and 60.1% (149) were determined to be ceftriaxone and ceftazidime resistant, respectively. Most of the Escherichia coli isolates were resistant to ceftriaxone (73%) and ceftazidime (65%), with 41 (65%) of the isolates showing resistance to both drugs. Of all the germs tested, 19% were Staphylococcus aureus, and of those, 23.4 percent were resistant to ceftriaxone and 33.4 percent to ceftazidime, respectively. Out of the bacterial strains that showed resistance to ceftriazone and ceftazidime, about 109 (44% of the total) were also resistant to two, three, or four additional medicines. In summary. More and more bacterial strains are showing resistance to thirdgeneration cephalosporins, such as ceftriaxone and ceftazidime. This indicates that the problem is becoming worse. Treatment may fail because some bacteria have shown multidrug resistance, especially to medicines used in clinical settings. Thus, antimicrobial susceptibility test results should inform the selection of suitable drugs for clinical usage
System metadata — ISO 26324:2025, Annex B · DOI Handbook 10.1
Each element by the standard's name (Annex B: reference elements, then administrative) and the Handbook's (in grey), read off the record above.
| Element | Value | In the record |
|---|---|---|
| DOI Name DOI name | 10.46243/jst.2025.v10.i6.pp37-47 | doi |
| Referent Type referentType | Creation | referent |
| Referent Sub-Type referentSubType | JournalArticle — an article in a journal | type |
| Referent Name(s) referentName(s) | AntimicrobialResistanceProfileofDifferentClinicalIsolatesagainstThird-GenerationCephalosporins (PrincipalTitle, en) | titles |
| Basic Metadata basicMetadata | author: DRBVRAMANA author: S.K.RUBINA author: DRMSANTOSHRAJA author: AHEMANTH author: S.AFREENJEHA publisher: Longman Publishers published: 2025-06-20 part of: Journal of Science & Technology · ISSN 2456-5660 · vol. 10 · no. 06 · pp. 37–47 language: en form: Digital · Visual · Language | agents, dates, container, language, structural_type, modes, characters |
| Referent Identifier(s) alternateIdentifier(s) | none besides the DOI | identifiers, relations (IsSameAs) |
| Registration Authority registrationAuthorityCode | Crossref — issued by Crossref (member 25296); held here as a copy | record.source_agency (our code, ra_doi_name, for names issued here once appointed) |
| Created Date issueDate | 2026-08-27 | record.registered (when the DOI name was first registered) |
| relatedIdentifiers | none needed — the descriptive metadata is in this record | container, relations (only where the descriptive metadata lives at another identifier) |
complete Every System Metadata element is here, with the basic metadata a journal article needs.
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History — the ledger
Every change to this DOI, in order, as it was recorded. Entries are only ever added, never changed or removed.
| # | When | What | By | Changes |
|---|---|---|---|---|
| 1 | 29 Sep 2026, 10:00 PM | register registered at Crossref; record read from api.crossref.org | Administrator (admin) | 177 fields set · sha256 8abb84e26be6… |
| 2 | 29 Sep 2026, 11:59 PM | update record re-read from api.crossref.org | Administrator (admin) | container.titles.0.value: |
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