Cite this DOI

DRBVRAMANA, S.K.RUBINA, DRMSANTOSHRAJA, AHEMANTH, & S.AFREENJEHA (2025). AntimicrobialResistanceProfileofDifferentClinicalIsolatesagainstThird-GenerationCephalosporins. *Journal of Science & Technology*, *10*(06), 37–47. https://doi.org/10.46243/jst.2025.v10.i6.pp37-47

@article{drbvramana2025antimicrobialresistanceprofileofdifferentclinicalisolatesagainstthirdgenerationcephalosporins,
  author    = {DRBVRAMANA and S.K.RUBINA and DRMSANTOSHRAJA and AHEMANTH and S.AFREENJEHA},
  title     = {{AntimicrobialResistanceProfileofDifferentClinicalIsolatesagainstThird-GenerationCephalosporins}},
  journal   = {Journal of Science \& Technology},
  year      = {2025},
  month     = {jun},
  volume    = {10},
  number    = {06},
  pages     = {37--47},
  publisher = {Longman Publishers},
  issn      = {2456-5660},
  doi       = {10.46243/jst.2025.v10.i6.pp37-47},
  url       = {https://doi.org/10.46243/jst.2025.v10.i6.pp37-47},
  language  = {en},
  abstract  = {death because they increase the likelihood of harmful treatment. Antimicrobial resistance statistics therefore aid in determining optimal patient care. Consequently, the purpose of this research was to examine the antimicrobial resistance pattern of third-generation cephalosporin medications at Jimma University Specialized Teaching Hospital. Methods. From April to August 2016, researchers at Jimma University Specialized Hospital (JUSH) performed a prospective cross-sectional study in a hospital setting. Patients in hospitals had their urine, sputum, wound swabs, and feces collected for clinical purposes. Following this, the usual microbiological procedures were followed in order to isolate and identify the bacterial species. Using the Kirby-Bauer disc diffusion technique, we tested the susceptibility of different microorganisms to antimicrobials. Final product. Out of a total of 248 bacterial isolates, 154 (62.1\%) were found in male patients and 94 (37.0\%) were found in female patients. Specimens were most often found to include Escherichia coli (25.4\% of the total) and Staphylococcus aureus (19.0\%). Approximately 56.5\% of the total bacterial isolates (140) and 60.1\% (149) were determined to be ceftriaxone and ceftazidime resistant, respectively. Most of the Escherichia coli isolates were resistant to ceftriaxone (73\%) and ceftazidime (65\%), with 41 (65\%) of the isolates showing resistance to both drugs. Of all the germs tested, 19\% were Staphylococcus aureus, and of those, 23.4 percent were resistant to ceftriaxone and 33.4 percent to ceftazidime, respectively. Out of the bacterial strains that showed resistance to ceftriazone and ceftazidime, about 109 (44\% of the total) were also resistant to two, three, or four additional medicines. In summary. More and more bacterial strains are showing resistance to thirdgeneration cephalosporins, such as ceftriaxone and ceftazidime. This indicates that the problem is becoming worse. Treatment may fail because some bacteria have shown multidrug resistance, especially to medicines used in clinical settings. Thus, antimicrobial susceptibility test results should inform the selection of suitable drugs for clinical usage}
}

TY  - JOUR
TI  - AntimicrobialResistanceProfileofDifferentClinicalIsolatesagainstThird-GenerationCephalosporins
AU  - DRBVRAMANA
AU  - S.K.RUBINA
AU  - DRMSANTOSHRAJA
AU  - AHEMANTH
AU  - S.AFREENJEHA
JO  - Journal of Science & Technology
PY  - 2025
DA  - 2025/06/20/
VL  - 10
IS  - 06
SP  - 37
EP  - 47
PB  - Longman Publishers
SN  - 2456-5660
LA  - en
AB  - death because they increase the likelihood of harmful treatment. Antimicrobial resistance statistics therefore aid in determining optimal patient care. Consequently, the purpose of this research was to examine the antimicrobial resistance pattern of third-generation cephalosporin medications at Jimma University Specialized Teaching Hospital. Methods. From April to August 2016, researchers at Jimma University Specialized Hospital (JUSH) performed a prospective cross-sectional study in a hospital setting. Patients in hospitals had their urine, sputum, wound swabs, and feces collected for clinical purposes. Following this, the usual microbiological procedures were followed in order to isolate and identify the bacterial species. Using the Kirby-Bauer disc diffusion technique, we tested the susceptibility of different microorganisms to antimicrobials. Final product. Out of a total of 248 bacterial isolates, 154 (62.1%) were found in male patients and 94 (37.0%) were found in female patients. Specimens were most often found to include Escherichia coli (25.4% of the total) and Staphylococcus aureus (19.0%). Approximately 56.5% of the total bacterial isolates (140) and 60.1% (149) were determined to be ceftriaxone and ceftazidime resistant, respectively. Most of the Escherichia coli isolates were resistant to ceftriaxone (73%) and ceftazidime (65%), with 41 (65%) of the isolates showing resistance to both drugs. Of all the germs tested, 19% were Staphylococcus aureus, and of those, 23.4 percent were resistant to ceftriaxone and 33.4 percent to ceftazidime, respectively. Out of the bacterial strains that showed resistance to ceftriazone and ceftazidime, about 109 (44% of the total) were also resistant to two, three, or four additional medicines. In summary. More and more bacterial strains are showing resistance to thirdgeneration cephalosporins, such as ceftriaxone and ceftazidime. This indicates that the problem is becoming worse. Treatment may fail because some bacteria have shown multidrug resistance, especially to medicines used in clinical settings. Thus, antimicrobial susceptibility test results should inform the selection of suitable drugs for clinical usage
DO  - 10.46243/jst.2025.v10.i6.pp37-47
UR  - https://doi.org/10.46243/jst.2025.v10.i6.pp37-47
ER  -

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    "title": "AntimicrobialResistanceProfileofDifferentClinicalIsolatesagainstThird-GenerationCephalosporins",
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    "abstract": "death because they increase the likelihood of harmful treatment. Antimicrobial resistance statistics therefore aid in determining optimal patient care. Consequently, the purpose of this research was to examine the antimicrobial resistance pattern of third-generation cephalosporin medications at Jimma University Specialized Teaching Hospital. Methods. From April to August 2016, researchers at Jimma University Specialized Hospital (JUSH) performed a prospective cross-sectional study in a hospital setting. Patients in hospitals had their urine, sputum, wound swabs, and feces collected for clinical purposes. Following this, the usual microbiological procedures were followed in order to isolate and identify the bacterial species. Using the Kirby-Bauer disc diffusion technique, we tested the susceptibility of different microorganisms to antimicrobials. Final product. Out of a total of 248 bacterial isolates, 154 (62.1%) were found in male patients and 94 (37.0%) were found in female patients. Specimens were most often found to include Escherichia coli (25.4% of the total) and Staphylococcus aureus (19.0%). Approximately 56.5% of the total bacterial isolates (140) and 60.1% (149) were determined to be ceftriaxone and ceftazidime resistant, respectively. Most of the Escherichia coli isolates were resistant to ceftriaxone (73%) and ceftazidime (65%), with 41 (65%) of the isolates showing resistance to both drugs. Of all the germs tested, 19% were Staphylococcus aureus, and of those, 23.4 percent were resistant to ceftriaxone and 33.4 percent to ceftazidime, respectively. Out of the bacterial strains that showed resistance to ceftriazone and ceftazidime, about 109 (44% of the total) were also resistant to two, three, or four additional medicines. In summary. More and more bacterial strains are showing resistance to thirdgeneration cephalosporins, such as ceftriaxone and ceftazidime. This indicates that the problem is becoming worse. Treatment may fail because some bacteria have shown multidrug resistance, especially to medicines used in clinical settings. Thus, antimicrobial susceptibility test results should inform the selection of suitable drugs for clinical usage",
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From the record as registered (version 2) — the record and its history. Programs: https://registry.smartscholars.in/api.php?action=cite&doi=10.46243%2Fjst.2025.v10.i6.pp37-47 gives all four in one JSON answer.