10.46243/jst.2022.v7.i05.pp179-184 registered
Molecular Screening & Influence of Cyp2C9*2 Variant with HHC in CVD Patients
Resolves to https://www.jst.org.in/index.php/pub/article/view/529
Held by Longman Publishers (India) · prefix 10.46243 live · DOI address https://doi.org/10.46243/jst.2022.v7.i05.pp179-184
Registered 29 Sep 2026 via crossref · record version 2 · last change 29 Sep 2026, 11:59 PM · record sha256 edad7f3dcba64edc…
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JournalArticle — an article in a journal · Digital · Visual · en
Molecular Screening & Influence of Cyp2C9*2 Variant with HHC in CVD Patients (PrincipalTitle)
Published 2023-07-18
Part of Journal of Science & Technology · ISSN 2456-5660 · volume 7 · issue 5 · pages 179–184
Agents
- Mehak Maryyam Mehak Maryyam (author)
- Longman Publishers (publisher)
Identifiers DOI 10.46243/jst.2022.v7.i05.pp179-184
Abstract
This study aimed to analyze the association of the CYP2C9*2 variant of the CYP2C9 family with hyperhomocysteinemia in cardiovascular patients. To carry out the research, genomic DNA was extracted from 100 hyperhomocysteinemic blood samples collected from KRL General Hospital and 40 control blood samples. Polymerase chain reaction and RFLP were performed on the selected hyperhomocysteinemic samples using AvaII restriction enzyme, and the results were analyzed on a gel documentation system. Among the three possible genotypes, CC, CT, and TT, only CC and CT were found in the study, with TT showing a frequency of zero. The calculated P value was 0.924, which was greater than the standard P value of 0.05, and the body mass index was found to be a major risk factor associated with cardiovascular diseases with a mean body mass index of 36.39. The allelic frequency of C was 0.86% and the frequency of the T allele was 0.13% in hyperhomocysteinemic patients. The findings conclude that there is no significant association between the CYP2C9*2 variant and elevated homocysteine levels in patients with cardiovascular diseases in the selected population.
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Each element by the standard's name (Annex B: reference elements, then administrative) and the Handbook's (in grey), read off the record above.
| Element | Value | In the record |
|---|---|---|
| DOI Name DOI name | 10.46243/jst.2022.v7.i05.pp179-184 | doi |
| Referent Type referentType | Creation | referent |
| Referent Sub-Type referentSubType | JournalArticle — an article in a journal | type |
| Referent Name(s) referentName(s) | Molecular Screening & Influence of Cyp2C9*2 Variant with HHC in CVD Patients (PrincipalTitle, en) | titles |
| Basic Metadata basicMetadata | author: Mehak Maryyam Mehak Maryyam publisher: Longman Publishers published: 2023-07-18 part of: Journal of Science & Technology · ISSN 2456-5660 · vol. 7 · no. 5 · pp. 179–184 language: en form: Digital · Visual · Language | agents, dates, container, language, structural_type, modes, characters |
| Referent Identifier(s) alternateIdentifier(s) | none besides the DOI | identifiers, relations (IsSameAs) |
| Registration Authority registrationAuthorityCode | Crossref — issued by Crossref (member 25296); held here as a copy | record.source_agency (our code, ra_doi_name, for names issued here once appointed) |
| Created Date issueDate | 2024-02-16 | record.registered (when the DOI name was first registered) |
| relatedIdentifiers | none needed — the descriptive metadata is in this record | container, relations (only where the descriptive metadata lives at another identifier) |
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History — the ledger
Every change to this DOI, in order, as it was recorded. Entries are only ever added, never changed or removed.
| # | When | What | By | Changes |
|---|---|---|---|---|
| 1 | 29 Sep 2026, 10:00 PM | register registered at Crossref; record read from api.crossref.org | Administrator (admin) | 115 fields set · sha256 9a86038bac4a… |
| 2 | 29 Sep 2026, 11:59 PM | update record re-read from api.crossref.org | Administrator (admin) | container.titles.0.value: titles.0.value: |
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