Cite this DOI

Mehak Maryyam, M. M. (2023). Molecular Screening & Influence of Cyp2C9*2 Variant with HHC in CVD Patients. *Journal of Science & Technology*, *7*(5), 179–184. https://doi.org/10.46243/jst.2022.v7.i05.pp179-184

@article{mehakmaryyam2023molecular,
  author    = {Mehak Maryyam, Mehak Maryyam},
  title     = {{Molecular Screening \& Influence of Cyp2C9*2 Variant with HHC in CVD Patients}},
  journal   = {Journal of Science \& Technology},
  year      = {2023},
  month     = {jul},
  volume    = {7},
  number    = {5},
  pages     = {179--184},
  publisher = {Longman Publishers},
  issn      = {2456-5660},
  doi       = {10.46243/jst.2022.v7.i05.pp179-184},
  url       = {https://doi.org/10.46243/jst.2022.v7.i05.pp179-184},
  language  = {en},
  abstract  = {This study aimed to analyze the association of the CYP2C9*2 variant of the CYP2C9 family with hyperhomocysteinemia in cardiovascular patients. To carry out the research, genomic DNA was extracted from 100 hyperhomocysteinemic blood samples collected from KRL General Hospital and 40 control blood samples. Polymerase chain reaction and RFLP were performed on the selected hyperhomocysteinemic samples using AvaII restriction enzyme, and the results were analyzed on a gel documentation system. Among the three possible genotypes, CC, CT, and TT, only CC and CT were found in the study, with TT showing a frequency of zero. The calculated P value was 0.924, which was greater than the standard P value of 0.05, and the body mass index was found to be a major risk factor associated with cardiovascular diseases with a mean body mass index of 36.39. The allelic frequency of C was 0.86\% and the frequency of the T allele was 0.13\% in hyperhomocysteinemic patients. The findings conclude that there is no significant association between the CYP2C9*2 variant and elevated homocysteine levels in patients with cardiovascular diseases in the selected population.}
}

TY  - JOUR
TI  - Molecular Screening & Influence of Cyp2C9*2 Variant with HHC in CVD Patients
AU  - Mehak Maryyam, Mehak Maryyam
JO  - Journal of Science & Technology
PY  - 2023
DA  - 2023/07/18/
VL  - 7
IS  - 5
SP  - 179
EP  - 184
PB  - Longman Publishers
SN  - 2456-5660
LA  - en
AB  - This study aimed to analyze the association of the CYP2C9*2 variant of the CYP2C9 family with hyperhomocysteinemia in cardiovascular patients. To carry out the research, genomic DNA was extracted from 100 hyperhomocysteinemic blood samples collected from KRL General Hospital and 40 control blood samples. Polymerase chain reaction and RFLP were performed on the selected hyperhomocysteinemic samples using AvaII restriction enzyme, and the results were analyzed on a gel documentation system. Among the three possible genotypes, CC, CT, and TT, only CC and CT were found in the study, with TT showing a frequency of zero. The calculated P value was 0.924, which was greater than the standard P value of 0.05, and the body mass index was found to be a major risk factor associated with cardiovascular diseases with a mean body mass index of 36.39. The allelic frequency of C was 0.86% and the frequency of the T allele was 0.13% in hyperhomocysteinemic patients. The findings conclude that there is no significant association between the CYP2C9*2 variant and elevated homocysteine levels in patients with cardiovascular diseases in the selected population.
DO  - 10.46243/jst.2022.v7.i05.pp179-184
UR  - https://doi.org/10.46243/jst.2022.v7.i05.pp179-184
ER  -

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    "DOI": "10.46243/jst.2022.v7.i05.pp179-184",
    "URL": "https://doi.org/10.46243/jst.2022.v7.i05.pp179-184",
    "title": "Molecular Screening & Influence of Cyp2C9*2 Variant with HHC in CVD Patients",
    "source": "Smart Scholars DOI Registry",
    "container-title": "Journal of Science & Technology",
    "author": [
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            "family": "Mehak Maryyam",
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    "volume": "7",
    "issue": "5",
    "page": "179-184",
    "publisher": "Longman Publishers",
    "language": "en",
    "abstract": "This study aimed to analyze the association of the CYP2C9*2 variant of the CYP2C9 family with hyperhomocysteinemia in cardiovascular patients. To carry out the research, genomic DNA was extracted from 100 hyperhomocysteinemic blood samples collected from KRL General Hospital and 40 control blood samples. Polymerase chain reaction and RFLP were performed on the selected hyperhomocysteinemic samples using AvaII restriction enzyme, and the results were analyzed on a gel documentation system. Among the three possible genotypes, CC, CT, and TT, only CC and CT were found in the study, with TT showing a frequency of zero. The calculated P value was 0.924, which was greater than the standard P value of 0.05, and the body mass index was found to be a major risk factor associated with cardiovascular diseases with a mean body mass index of 36.39. The allelic frequency of C was 0.86% and the frequency of the T allele was 0.13% in hyperhomocysteinemic patients. The findings conclude that there is no significant association between the CYP2C9*2 variant and elevated homocysteine levels in patients with cardiovascular diseases in the selected population.",
    "ISSN": "2456-5660"
}

From the record as registered (version 2) — the record and its history. Programs: https://registry.smartscholars.in/api.php?action=cite&doi=10.46243%2Fjst.2022.v7.i05.pp179-184 gives all four in one JSON answer.