10.46243/jst.2023.v8.i02.pp26-63 registered
From Zine Balance to Disense Progression: Decoding the Puzzle of Neurodegeneration
Resolves to https://www.jst.org.in/index.php/pub/article/view/1446
Held by Longman Publishers (India) · prefix 10.46243 live · DOI address https://doi.org/10.46243/jst.2023.v8.i02.pp26-63
Registered 29 Sep 2026 via crossref · record version 2 · last change 30 Sep 2026, 12:00 AM · record sha256 1661fa652efef696…
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What the DOI identifies
JournalArticle — an article in a journal · Digital · Visual · en
From Zine Balance to Disense Progression: Decoding the Puzzle of Neurodegeneration (PrincipalTitle)
Published 2023-02-26
Part of Journal of Science & Technology · ISSN 2456-5660 · volume 08 · issue 02 · pages 26–63
Agents
- N. Danamurthy (author)
- T. Sujatha (author)
- K. Ravindranadh (author)
- M. Sushma (author)
- Longman Publishers (publisher)
Identifiers DOI 10.46243/jst.2023.v8.i02.pp26-63
Abstract
A vital trace element in the human body, zinc is involved in many physiological functions, including DNA repair, neurotransmission, oxidative stress, and protein synthesis. Intracellular zinc is exported by members of the zinc transporters (ZnTs) family, while extracellular zinc is imported by Zrt-and-Irt-like proteins (ZIPs). The preservation of cellular zinc homeostasis depends on these mechanisms. Neurodegenerative disorders have been associated with imbalances in zinc metabolism. Through processes like ferroptosis, protein phase separation, oxidative stress, neuroinflammation, and cell death control, zinc level disruptions may affect the survival and function of neurons and consequently contribute to the development of neurodegenerative disorders. Our knowledge of the pathophysiology of these illnesses may thus be improved by doing a thorough analysis of the regulatory network of zinc and looking into the connection between neurodegenerative disorders and zinc dysmetabolism. Furthermore, it could provide new perspectives and methods for treating neurodegenerative illnesses.
System metadata — ISO 26324:2025, Annex B · DOI Handbook 10.1
Each element by the standard's name (Annex B: reference elements, then administrative) and the Handbook's (in grey), read off the record above.
| Element | Value | In the record |
|---|---|---|
| DOI Name DOI name | 10.46243/jst.2023.v8.i02.pp26-63 | doi |
| Referent Type referentType | Creation | referent |
| Referent Sub-Type referentSubType | JournalArticle — an article in a journal | type |
| Referent Name(s) referentName(s) | From Zine Balance to Disense Progression: Decoding the Puzzle of Neurodegeneration (PrincipalTitle, en) | titles |
| Basic Metadata basicMetadata | author: N. Danamurthy author: T. Sujatha author: K. Ravindranadh author: M. Sushma publisher: Longman Publishers published: 2023-02-26 part of: Journal of Science & Technology · ISSN 2456-5660 · vol. 08 · no. 02 · pp. 26–63 language: en form: Digital · Visual · Language | agents, dates, container, language, structural_type, modes, characters |
| Referent Identifier(s) alternateIdentifier(s) | none besides the DOI | identifiers, relations (IsSameAs) |
| Registration Authority registrationAuthorityCode | Crossref — issued by Crossref (member 25296); held here as a copy | record.source_agency (our code, ra_doi_name, for names issued here once appointed) |
| Created Date issueDate | 2026-09-18 | record.registered (when the DOI name was first registered) |
| relatedIdentifiers | none needed — the descriptive metadata is in this record | container, relations (only where the descriptive metadata lives at another identifier) |
complete Every System Metadata element is here, with the basic metadata a journal article needs.
The System Metadata Declaration (JSON) · the Kernel Metadata Declaration (XML) · what each sub-type needs
History — the ledger
Every change to this DOI, in order, as it was recorded. Entries are only ever added, never changed or removed.
| # | When | What | By | Changes |
|---|---|---|---|---|
| 1 | 29 Sep 2026, 10:00 PM | register registered at Crossref; record read from api.crossref.org | Administrator (admin) | 221 fields set · sha256 a32c333513de… |
| 2 | 30 Sep 2026, 12:00 AM | update record re-read from api.crossref.org | Administrator (admin) | container.titles.0.value: |
Machine-readable: the history as JSON, with the full record after each change.
