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10.46243/jst.2021.v6.i3.pp97-101 registered

A Review on RP-HPLC Method Development and Validation for Bulk Dosage Form

Resolves to https://www.jst.org.in/index.php/pub/article/view/825

Held by Longman Publishers (India) · prefix 10.46243 live · DOI address https://doi.org/10.46243/jst.2021.v6.i3.pp97-101

Registered 29 Sep 2026 via crossref · record version 2 · last change 30 Sep 2026, 12:00 AM · record sha256 298e45c89ad5e224…

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What the DOI identifies

JournalArticle — an article in a journal · Digital · Visual · en

A Review on RP-HPLC Method Development and Validation for Bulk Dosage Form (PrincipalTitle)

Published 2021-05-28

Part of Journal of Science & Technology · ISSN 2456-5660 · volume 06 · issue 03 · pages 97–101

Agents

  • Bhavsar Prachi Pravin (author)
  • Kolhe Madhuri S. (author)
  • Mrs. Jadhav Prerana B (author)
  • Longman Publishers (publisher)

Identifiers DOI 10.46243/jst.2021.v6.i3.pp97-101

Abstract

Chromatography, although primarily a separation technique, is mostly employed in chemical analysis in which High-performance liquid chromatography (HPLC) is an extremely versatile technique where analytes are separated by passage through a column packed with micro meter-sized particles. Now a day reversed-phase chromatography is the most commonly used separation technique in HPLC. The reasons for this include the simplicity, versatility, and scope of the reversed-phase method as it is able to handle compounds of a diverse polarity and molecular mass. Reversed phase chromatography has found both analytical and preparative applications in the area of biochemical separation and purification. Molecules that possess some degree of hydrophobic character, such as proteins, peptides and nucleic acids, can be separated by reversed phase chromatography with excellent recovery and resolution. This review covers the importance of RP-HPLC in analytical method development and their strategies along with brief knowledge of critical chromatographic parameters need to be optimized for an efficient method development.

Licence https://creativecommons.org/licenses/by/4.0/

System metadata — ISO 26324:2025, Annex B · DOI Handbook 10.1

Each element by the standard's name (Annex B: reference elements, then administrative) and the Handbook's (in grey), read off the record above.

ElementValueIn the record
DOI Name
DOI name
10.46243/jst.2021.v6.i3.pp97-101doi
Referent Type
referentType
Creationreferent
Referent Sub-Type
referentSubType
JournalArticle — an article in a journaltype
Referent Name(s)
referentName(s)
A Review on RP-HPLC Method Development and Validation for Bulk Dosage Form (PrincipalTitle, en)titles
Basic Metadata
basicMetadata
author: Bhavsar Prachi Pravin
author: Kolhe Madhuri S.
author: Mrs. Jadhav Prerana B
publisher: Longman Publishers
published: 2021-05-28
part of: Journal of Science & Technology · ISSN 2456-5660 · vol. 06 · no. 03 · pp. 97–101
language: en
form: Digital · Visual · Language
agents, dates, container, language, structural_type, modes, characters
Referent Identifier(s)
alternateIdentifier(s)
none besides the DOIidentifiers, relations (IsSameAs)
Registration Authority
registrationAuthorityCode
Crossref — issued by Crossref (member 25296); held here as a copyrecord.source_agency (our code, ra_doi_name, for names issued here once appointed)
Created Date
issueDate
2026-09-12record.registered (when the DOI name was first registered)
relatedIdentifiersnone needed — the descriptive metadata is in this recordcontainer, relations (only where the descriptive metadata lives at another identifier)

complete Every System Metadata element is here, with the basic metadata a journal article needs.

The System Metadata Declaration (JSON) · the Kernel Metadata Declaration (XML) · what each sub-type needs

History — the ledger

Every change to this DOI, in order, as it was recorded. Entries are only ever added, never changed or removed.

#WhenWhatByChanges
129 Sep 2026, 10:00 PMregister
registered at Crossref; record read from api.crossref.org
Administrator (admin) 115 fields set · sha256 fc1d1995df60…
230 Sep 2026, 12:00 AMupdate
record re-read from api.crossref.org
Administrator (admin)
container.titles.0.value: Journal of Science & Technology → Journal of Science & Technology

Machine-readable: the history as JSON, with the full record after each change.

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