{ "ok": true, "doi": "10.46243/jstj.2020.v5.i2.312", "doi_display": "10.46243/jstj.2020.v5.i2.312", "doi_url": "https://doi.org/10.46243/jstj.2020.v5.i2.312", "state": "registered", "url": "https://www.jst.org.in/index.php/pub/article/view/312", "title": "Development and Validation of New UV-Spectrophotometric Method for The Quantitation of Retigabine In Pure and Formulations", "version": 2, "registered_via": "crossref", "prefix": { "prefix": "10.46243", "status": "live" }, "registrant": { "name": "Longman Publishers", "kind": "publisher", "country": "India" }, "reserved_at": null, "registered_at": "2026-09-29 22:00:37", "updated_at": "2026-09-29 23:59:57", "withdrawn_at": null, "withdrawn_reason": null, "record": { "format": "smartscholars-doi-metadata/1.0", "doi": "10.46243/jstj.2020.v5.i2.312", "referent": "Creation", "type": "JournalArticle", "structural_type": "Digital", "modes": [ "Visual" ], "characters": [ "Language" ], "titles": [ { "value": "Development and Validation of New UV-Spectrophotometric Method for The Quantitation of Retigabine In Pure and Formulations", "type": "PrincipalTitle", "lang": "en" } ], "identifiers": [ { "type": "DOI", "value": "10.46243/jstj.2020.v5.i2.312" } ], "agents": [ { "role": "author", "name": { "given": "Venkateswara", "family": "ReddyBilla" }, "sequence": "first" }, { "role": "author", "name": { "given": "Naveen", "family": "ReddySeelam" }, "sequence": "additional" }, { "role": "publisher", "name": { "org": "Longman Publishers" } } ], "dates": { "published": "2020", "date_type": "PublicationDate", "online": "2020" }, "language": "en", "container": { "type": "Journal", "titles": [ { "value": "Journal of Science & Technology", "type": "PrincipalTitle" } ], "identifiers": [ { "type": "ISSN", "value": "2456-5660", "medium": "electronic" } ], "volume": "05", "issue": "02", "pages": { "first": "99", "last": "103" } }, "links": [ { "url": "https://www.jst.org.in/index.php/pub/article/view/312", "return_type": "text/html", "primary": true }, { "url": "https://www.jst.org.in/index.php/pub/article/download/312/273", "purpose": "text-mining", "return_type": "application/pdf" }, { "url": "https://www.jst.org.in/index.php/pub/article/download/312/1319", "purpose": "text-mining", "return_type": "application/xml" }, { "url": "https://www.jst.org.in/index.php/pub/article/view/312/273", "purpose": "similarity-checking" } ], "abstract": { "value": "A simple, accurate, precise, economical and reproducible UV-spectrophotometric method has been developed for the simultaneous estimation of Retigabinein bulk and in combined tablet dosage form. The stock solutions were prepared in methanol followed by the further required dilutions with distilled water. This method involves the formation and solving of simultaneous equations at 254nm as absorbance maxima of Retigabinerespectively. Linearityobeyed the concentration range of 25μg/mLto 75μg/mL for Retigabinerespectively. The results of analysis were validated statistically and by recovery studies. The % RSD for the recovery study was less than 2.0.The proposed method can be effectively applied for the estimation of Retigabinein bulk and in combined tablet dosage form", "lang": "en" }, "license": { "url": "https://creativecommons.org/licenses/by/4.0/", "start": "2020-01-01", "applies_to": "vor" }, "references": [ { "key": "ref1", "unstructured": "Satyanarayana, P.V.V., Alavala siva madhavi., New spectrophotometric methods for the quantitative estimation of ezogabine in formulation. International Journal of Research in Pharmacy and Chemistry 2012, 2, 4, 1093-1098" }, { "key": "ref2", "unstructured": "Ravisankar panchamorthy., Lokaparani, C. H., Devadasu, C.H.,Srinivasa babu, P., Novel sensitive spectrophotometric methods for determination of retigabine in bulk and pharmaceutical formulation, International Journal of Pharma Science. 2014, 4, 6, 773- 779" }, { "key": "ref3", "unstructured": "Lakshmi, B., Saraswathi, K., Reddy, T.V., RP-HPLC method development and validation for the analysis of ezogabine in pharmaceutical dosage form Int.J.A.PS.BMS, 2012, 1, 1, 7- 14" }, { "key": "ref4", "unstructured": "Satyanarayana, P.V.V., Alavala Siva Madhavi., Validated RP HPLC method for the estimation of ezogabine in tablet dosage form, International Journal of Research in Pharmaceutical and Biomedical Sciences, 2012, 3, 2, 955-959" }, { "key": "ref5", "doi": "10.1016/j.jpba.2012.07.035", "unstructured": "Wang, X., Zhou, H., Zheng, J., Huang, C., Liu, W., Yu, L., Zeng, S.,Identification and characterization of four process-related impurities in retigabine. 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J.Sci.Res.Phar.2013,2,4,1-6" }, { "key": "ref9", "unstructured": "Xifeng Wu., Feng Shao., Chunlei Tao., Jie Li., Development and validation of simple stability indicating HPLC method for the determination of retigabine and related substances in drug substances. J. Chin. Pharm. Sci. 2015, 24, 4, 241-249" } ], "record": { "registrant": "Longman Publishers", "registered": "2026-09-08", "updated": "2026-09-17", "issue_number": 1, "source": "crossref-api", "source_agency": "Crossref (member 25296)" } }, "record_sha256": "45467abedbc3a1b4a6df54fe20b4a630bc68ce6f3e1d23455b2cffc76823c51b", "handle": { "synced_at": "2026-10-01 18:13:41", "url": "https://www.jst.org.in/index.php/pub/article/view/312" }, "links": { "record_page": "https://registry.smartscholars.in/record.php?doi=10.46243%2Fjstj.2020.v5.i2.312", "system_metadata": "https://registry.smartscholars.in/resolve.php?doi=10.46243%2Fjstj.2020.v5.i2.312&as=system", "history": "https://registry.smartscholars.in/api.php?action=history&doi=10.46243%2Fjstj.2020.v5.i2.312", "kernel_xml": "https://registry.smartscholars.in/resolve.php?doi=10.46243%2Fjstj.2020.v5.i2.312&as=xml" } }