{ "ok": true, "doi": "10.46243/jst.2022.v7.i08.pp01-08", "doi_display": "10.46243/jst.2022.v7.i08.pp01-08", "doi_url": "https://doi.org/10.46243/jst.2022.v7.i08.pp01-08", "state": "registered", "url": "https://www.jst.org.in/index.php/pub/article/view/813", "title": "In Silico study using Toxtree (TT) Cramer decision tree scheme for different Isomers of Resmethrin -a Type-I Synthetic Pyrethroid", "version": 2, "registered_via": "crossref", "prefix": { "prefix": "10.46243", "status": "live" }, "registrant": { "name": "Longman Publishers", "kind": "publisher", "country": "India" }, "reserved_at": null, "registered_at": "2026-09-29 22:00:23", "updated_at": "2026-09-29 23:59:41", "withdrawn_at": null, "withdrawn_reason": null, "record": { "format": "smartscholars-doi-metadata/1.0", "doi": "10.46243/jst.2022.v7.i08.pp01-08", "referent": "Creation", "type": "JournalArticle", "structural_type": "Digital", "modes": [ "Visual" ], "characters": [ "Language" ], "titles": [ { "value": "In Silico study using Toxtree (TT) Cramer decision tree scheme for different Isomers of Resmethrin -a Type-I Synthetic Pyrethroid", "type": "PrincipalTitle", "lang": "en" } ], "identifiers": [ { "type": "DOI", "value": "10.46243/jst.2022.v7.i08.pp01-08" } ], "agents": [ { "role": "author", "name": { "given": "Manju Mehta", "family": "Manju Mehta" }, "sequence": "first" }, { "role": "publisher", "name": { "org": "Longman Publishers" } } ], "dates": { "published": "2022-10-27", "date_type": "PublicationDate", "online": "2022-10-27" }, "language": "en", "container": { "type": "Journal", "titles": [ { "value": "Journal of Science & Technology", "type": "PrincipalTitle" } ], "identifiers": [ { "type": "ISSN", "value": "2456-5660", "medium": "electronic" } ], "volume": "7", "issue": "8", "pages": { "first": "1", "last": "8" } }, "links": [ { "url": "https://www.jst.org.in/index.php/pub/article/view/813", "return_type": "text/html", "primary": true }, { "url": "https://www.jst.org.in/index.php/pub/article/download/813/741", "purpose": "text-mining", "return_type": "application/pdf" }, { "url": "https://www.jst.org.in/index.php/pub/article/download/813/2021", "purpose": "text-mining", "return_type": "application/xml" }, { "url": "https://jst.org.in/admin/uploads/JST070801.pdf", "purpose": "similarity-checking" } ], "abstract": { "value": "Synthetic pyrethroids are widely used in household, public places and agriculture as insecticides but have harmful effect on human and the environment . The Cramer classification scheme (decision tree) is the best-known approach to estimate the Threshold of Toxicological Concern for a chemical substance based on its chemical structure. In present article we have used In silico tool Toxtree to get the Cramer class for isomers of Resmethrin. The stereochemical relationships and toxicologic and environmental effects are also discussed", "lang": "en" }, "license": { "url": "https://creativecommons.org/licenses/by/4.0/", "start": "2022-10-27", "applies_to": "vor" }, "references": [ { "key": "ref1", "unstructured": "Casida J.E., Pyrethrum, the Natural Insecticide, Academic Press, New York-London (1973)" }, { "key": "ref2", "doi": "10.1002/ps.2780270403", "unstructured": "Elliott, M. (1989). The pyrethroids: early discovery, recent advances and the future. Pesticide Science, 27(4), 337-351" }, { "key": "ref3", "doi": "10.1039/cs9780700473", "unstructured": "Elliott M., Janes N. F.,Chem Soc. 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In Mode of Action, Metabolism and Toxicology (pp.485-490).Pergamon" }, { "key": "ref19", "doi": "10.1016/0048-3575(80)90127-3", "unstructured": "Gray, A. J., Connors, T. A., & Hoellinger, H. (1980). The relationship between the pharmacokinetics of intravenous cismethrin and bioresmethrin and their mammalian toxicity. Pesticide Biochemistry and Physiology, 13(3), 281-293" }, { "key": "ref20", "doi": "10.1016/j.ntt.2007.10.005", "unstructured": "Wolansky, M. J., & Harrill, J. A. (2008). Neurobehavioral toxicology of pyrethroid insecticides in adult animals: a critical review. Neurotoxicology and teratology, 30(2), 55-78" }, { "key": "ref21", "doi": "10.1016/0048-3575(76)90060-2", "unstructured": "White, I. N. H., Verschoyle, R. D., Moradian, M. H., & Barnes, J. M. (1976). The relationship between brain levels of cismethrin and bioresmethrin in female rats and neurotoxic effects. Pesticide Biochemistry and Physiology, 6(5), 491-500" }, { "key": "ref22", "doi": "10.1016/s0015-6264(76)80522-6", "unstructured": "Cramer G. M., R. A. Ford, R. L. Hall, Estimation of Toxic Hazard-A Decision Tree Approach, J. Cosmet. Toxicol., Vol.16, pp. 255-276, Pergamon Press, 1978 http://toxtree.sourceforge.net/cramer3.html" }, { "key": "ref23", "doi": "10.1016/s0278-6915(96)00049-x", "unstructured": "I.C. Munro, R.A. Ford, E. Kennepohl, and J.G. Sprenger, Correlation of structural class with No-Observed-Effect Levels: A proposal for establishing a threshold of concern, Food Chem. Toxicol. 34 (1996), pp. 829-867" }, { "key": "ref24", "doi": "10.1080/10629360802083871", "unstructured": "Patlewicz G, Jeliazkova N, Safford RJ, Worth AP, Aleksiev B. (2008) A n evaluation of the implementation of the Cramer classification scheme in the Toxtree software. SAR QSAR Environ Res.;19(5-6):495-524" } ], "record": { "registrant": "Longman Publishers", "registered": "2024-02-16", "updated": "2026-09-17", "issue_number": 1, "source": "crossref-api", "source_agency": "Crossref (member 25296)" } }, "record_sha256": "f3ba849d6e27b134cfd6de011484f6876bed2b36d4c8bebc25e198e29c8c3385", "handle": { "synced_at": "2026-10-01 18:12:30", "url": "https://www.jst.org.in/index.php/pub/article/view/813" }, "links": { "record_page": "https://registry.smartscholars.in/record.php?doi=10.46243%2Fjst.2022.v7.i08.pp01-08", "system_metadata": "https://registry.smartscholars.in/resolve.php?doi=10.46243%2Fjst.2022.v7.i08.pp01-08&as=system", "history": "https://registry.smartscholars.in/api.php?action=history&doi=10.46243%2Fjst.2022.v7.i08.pp01-08", "kernel_xml": "https://registry.smartscholars.in/resolve.php?doi=10.46243%2Fjst.2022.v7.i08.pp01-08&as=xml" } }