Cite this DOI

Longman Publishers (2020). Formulation and Characterization of Tranylcypromine loaded Polymeric Micellar In-Situ Nasal Gel for treatment of Depression. *Journal of Science & Technology*, 149–165. https://doi.org/10.46243/jst.2020.v5.i4.pp149-165

@article{anon2020formulation,
  title     = {{Formulation and Characterization of Tranylcypromine loaded Polymeric Micellar In-Situ Nasal Gel for treatment of Depression}},
  journal   = {Journal of Science \& Technology},
  year      = {2020},
  month     = {jul},
  number    = {Volume 5},
  pages     = {149--165},
  publisher = {Longman Publishers},
  issn      = {2456-5660},
  doi       = {10.46243/jst.2020.v5.i4.pp149-165},
  url       = {https://doi.org/10.46243/jst.2020.v5.i4.pp149-165},
  language  = {en},
  abstract  = {:Tranylcypromine is a drug used as antidepressant,anxiolytic, nonselective MAO A/B inhibitor. This drug is used to treat depression.The research was conducted to develop a polymeric micelle using a block copolymer, Pluronic F-68 and Gelucire 50/13 to improve the permeability of Tranylcypromine (TCP). A direct dissolution method was used to prepare polymeric micelles. The prepared micelles were characterised for particle size, \% EE, zeta potential, in-vitro release. These micelles solution was used to prepare in situ gel by cold method in order to achieve controlled release. Central composite design was used for optimization of both polymeric micelles and insitu nasal gel.The main objective of this research work is to develop formulation acting centrally without undergoing first pass metabolism i.ie. directly nasal to brain delivery route.}
}

TY  - JOUR
TI  - Formulation and Characterization of Tranylcypromine loaded Polymeric Micellar In-Situ Nasal Gel for treatment of Depression
JO  - Journal of Science & Technology
PY  - 2020
DA  - 2020/07/30/
IS  - Volume 5
SP  - 149
EP  - 165
PB  - Longman Publishers
SN  - 2456-5660
LA  - en
AB  - :Tranylcypromine is a drug used as antidepressant,anxiolytic, nonselective MAO A/B inhibitor. This drug is used to treat depression.The research was conducted to develop a polymeric micelle using a block copolymer, Pluronic F-68 and Gelucire 50/13 to improve the permeability of Tranylcypromine (TCP). A direct dissolution method was used to prepare polymeric micelles. The prepared micelles were characterised for particle size, % EE, zeta potential, in-vitro release. These micelles solution was used to prepare in situ gel by cold method in order to achieve controlled release. Central composite design was used for optimization of both polymeric micelles and insitu nasal gel.The main objective of this research work is to develop formulation acting centrally without undergoing first pass metabolism i.ie. directly nasal to brain delivery route.
DO  - 10.46243/jst.2020.v5.i4.pp149-165
UR  - https://doi.org/10.46243/jst.2020.v5.i4.pp149-165
ER  -

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    "type": "article-journal",
    "id": "10.46243/jst.2020.v5.i4.pp149-165",
    "DOI": "10.46243/jst.2020.v5.i4.pp149-165",
    "URL": "https://doi.org/10.46243/jst.2020.v5.i4.pp149-165",
    "title": "Formulation and Characterization of Tranylcypromine loaded Polymeric Micellar In-Situ Nasal Gel for treatment of Depression",
    "source": "Smart Scholars DOI Registry",
    "container-title": "Journal of Science & Technology",
    "issued": {
        "date-parts": [
            [
                2020,
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    "issue": "Volume 5",
    "page": "149-165",
    "publisher": "Longman Publishers",
    "language": "en",
    "abstract": ":Tranylcypromine is a drug used as antidepressant,anxiolytic, nonselective MAO A/B inhibitor. This drug is used to treat depression.The research was conducted to develop a polymeric micelle using a block copolymer, Pluronic F-68 and Gelucire 50/13 to improve the permeability of Tranylcypromine (TCP). A direct dissolution method was used to prepare polymeric micelles. The prepared micelles were characterised for particle size, % EE, zeta potential, in-vitro release. These micelles solution was used to prepare in situ gel by cold method in order to achieve controlled release. Central composite design was used for optimization of both polymeric micelles and insitu nasal gel.The main objective of this research work is to develop formulation acting centrally without undergoing first pass metabolism i.ie. directly nasal to brain delivery route.",
    "ISSN": "2456-5660"
}

From the record as registered (version 2) — the record and its history. Programs: https://registry.smartscholars.in/api.php?action=cite&doi=10.46243%2Fjst.2020.v5.i4.pp149-165 gives all four in one JSON answer.