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Archives of Applied Science Research, 5, (6): 227-231, (2013)" }, { "path": "references.6.doi", "from": null, "to": "10.1177/1747519819893885" }, { "path": "references.6.key", "from": null, "to": "ref7" }, { "path": "references.6.unstructured", "from": null, "to": "Fahmi1, N., Upadhyay, M., Sharma, N. and Belwal, S. Synthesis, characterization and biochemical behaviour of macrocyclic complexes of Zn(II) and Co(II) metals. Journal of Chemical ResearchVol. 44, (5-6) 336–342, (2020)" }, { "path": "references.7.doi", "from": null, "to": "10.4067/s0717-97072017000403731" }, { "path": "references.7.key", "from": null, "to": "ref8" }, { "path": "references.7.unstructured", "from": null, "to": "Esmaiel, S., Sayed, Ali, N. T. and Mohsen, S. Synthesis, characterization, theoretical and biological studies of a new macrocyclicSchiff base with Co(II), Ni(II), Cu(II) and Zn(II) complexes J. Chil. Chem. 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The Schiff base ligand was prepared by the condensation of 1-(5-bromo-2-hydroxyphenyl)-3-(furan-2-yl)propane-1,3-dione with o-phenylenediamine. The synthesized metal complexes were characterized by conductivity, UV–Visible, FTIR, ^1H NMR, TGA-DTA, and XRD analyses. The results indicated that all the complexes are non-electrolytic in nature and exhibit a hexadentate coordination mode through four nitrogen atoms of the azomethine groups. The ligand and its metal complexes were evaluated in vitro for their antibacterial and antifungal activities against selected microorganisms using Gentamycin, Ampicillin, Chloramphenicol, Ciprofloxacin, Norfloxacin, Nystatin, and Griseofulvin as standard drugs. The synthesized complexes demonstrated higher biological activities than the corresponding standard drugs, indicating their potential antimicrobial properties.", "lang": "en" }, "license": { "url": "https://creativecommons.org/licenses/by/4.0/", "start": "2022-05-22", "applies_to": "vor" }, "references": [ { "key": "ref1", "unstructured": "Jayaseelan, P., Prasad, S. Synthesis, spectral characterization, electrochemical and anti-microbial activities" }, { "key": "ref2", "doi": "10.1080/15533174.2016.1186091", "unstructured": "Shakir, M., Bano N., Rauf, A., Kazmi, S. and Alam, M. Synthesis and characterization of pharmacologically active 18-membered tetraamide macrocyclic complexes of Mn(II), Co(II), Ni(II), Cu(II), and Zn(II): In-vitro antimicrobial, anticancer screening, DNA interaction and docking studies Inorg. Nano-Met. Chem. 47, 576, (2017)" }, { "key": "ref3", "doi": "10.2298/jsc090408009m", "unstructured": "Munde, A., Jagdale A., Jadhav, S., Chondhekar, T. Synthesis, characterization and thermal study of some transition metal complexes of an asymmetrical tetradentate Schiff base ligand. J. Serb. Chem. Soc.75, (3): 349-359, (2010)" }, { "key": "ref4", "doi": "10.1016/j.saa.2013.09.124", "unstructured": "Tyagi, M., Chandra, S., Akhatar, J., Chand, D. “Modern spectroscopic techniquein the characterization of bio sensitive macrocyclic Schiff base ligand and its complexes.Inhibitory activity against plant pathogenic fungi”. Spectrochimica Acta. Part A Molecularand Bimolecular Spectroscopy. (118): 1056-1060, (2014)" }, { "key": "ref5", "doi": "10.1016/j.saa.2015.02.006", "unstructured": "Shankarwar, S. Shelke, V. Chondhekar, T. Synthesis, spectral, thermal and antimicrobial studies of transition metal complexes of 14- membered tetraaza [N ] macrocyclic ligand. Spectrochimica Acta. Part A 4 Molecular and Bimolecular Spectroscopy, (145): 188-193, (2015)" }, { "key": "ref6", "unstructured": "Chaudhary, N. K. In vitro antibacterial studies of some transition metal complex of Schiff base derived from 2-aminophenol and furan-2-carbaldehyde. Archives of Applied Science Research, 5, (6): 227-231, (2013)" }, { "key": "ref7", "doi": "10.1177/1747519819893885", "unstructured": "Fahmi1, N., Upadhyay, M., Sharma, N. and Belwal, S. Synthesis, characterization and biochemical behaviour of macrocyclic complexes of Zn(II) and Co(II) metals. Journal of Chemical ResearchVol. 44, (5-6) 336–342, (2020)" }, { "key": "ref8", "doi": "10.4067/s0717-97072017000403731", "unstructured": "Esmaiel, S., Sayed, Ali, N. T. and Mohsen, S. Synthesis, characterization, theoretical and biological studies of a new macrocyclicSchiff base with Co(II), Ni(II), Cu(II) and Zn(II) complexes J. Chil. Chem. Soc., 62, N-4, (2017)" }, { "key": "ref9", "doi": "10.1007/s12039-017-1398-8", "unstructured": "Shakir, M., Bano, N., Rauf, M., and Owais, MPharmacologically significant tetraaza macrocyclic metalcomplexes derived from isatin and 3,4-diaminobenzophenone: Synthesis, spectral studies and comparative in vitro biological assessment J. Chem. Sci. Vol. 129, No. 12,, pp. 1905–1920, (2017). Published by: Longman Publishers www.jst.org.in P age 66 | 9" }, { "key": "ref10", "unstructured": "Mishra, R. M., Pandey, S., Saxena, R. “Homozygous hemoglobin D with alpha thalassemia: case report,” The Open Hematology Journal, Vol. (2): 1–4, (2011)" }, { "key": "ref11", "doi": "10.22214/ijraset.2019.1103", "unstructured": "Lawrence, K. Leo, Angelo, A.N. Paul. Synthesis, characterization and antibacterial activity of chiral 1, 1’ – (4, 6–dihydroxy–1, 3-phenylene) bisethanone based tetraaza macrocyclic Co (II), Ni (II), Cu (II) and Zn (II) metal complexes. International Journal of Research and Analytical Reviews Volume 6, Issue (1), 195- 205, (2019)" }, { "key": "ref12", "doi": "10.1007/s10847-016-0649-5", "unstructured": "El-Boraey, HA, El-Salamony, MA and Hathout AA. J. Incl. Phenom Macrocycl Chem. 86: 153. (2016)" }, { "key": "ref13", "doi": "10.1016/s0928-0987(02)00077-5", "unstructured": "Ajit, K. C., Pandeya, S. N., “Synthesis and anticonvulsant activity (chemoshock) of Schiff and Mannich bases of isatin derivatives with 2-amino pyridine (mechanism of action),” International Journal of Pharm. Tech. Research, Vol. 4, No. (2): 590–598, (2012)" }, { "key": "ref14", "unstructured": "Manchanda, D., Sidhu, A., Gumber, Kaur K. Synthesis and antifungal potential of some transition metal complexes of tridentate N-Benzylidenepyridine-2, 6-Diamine. Int. J. of Chemical Studies, 5, (2): 455- 2 459, (2017)" }, { "key": "ref15", "unstructured": "Sakhare, M., Lande, M., Arbad, B. Synthesis, characterization and antimicrobial studies on La(III), Ce(III) and Pr(III) complexes with a tetraaza macrocyclic Ligand, Advances in Applied Science Research. 4, (1): 94-100, (2013)" }, { "key": "ref16", "doi": "10.18535/ijetst/v4i9.01", "unstructured": "Jisha, M. J., Isac, C. Sobana, R. Synthesis and characterization of Schiff base complexes of Cu(II), Ni(II), Co(II) complexes of Schiff base derived from furan 3- carboxaldehyde and 3- amino pyridine International Journal of Scientific and Research Publications, Vol. 7, Issue (10): 10-19, (2017)" }, { "key": "ref17", "doi": "10.2298/jsc090804069c", "unstructured": "Chandra, S. Tyagi, M. and Agrwal, S., Synthesis, and characterization of tetraaza macrocyclic ligand and its Cobalt(II), Nickel(II,) Copper(II) complexes, J. of Serb. Chem. Soc. 75. (7): 935-941, (2010)" }, { "key": "ref18", "unstructured": "Kalsi, P. S. Spectroscopy of Organic Compounds, New Age International (P) Ltd., New Delhi, India, (1999)" }, { "key": "ref19", "doi": "10.31788/rjc.2018.1123033", "unstructured": "Vijayalakshmi, M., Synthesis and spectral characterization of Schiff base transition metal complexes, DNA cleavage and antibacterial activity studies,Rasayan J. of Chem. 11, (2): 857–864, (2018)" }, { "key": "ref20", "unstructured": "Gunvanthrao, N. Hire, B. Mruthyunjayaswamy, M. Metal (II) complexes of ONO donor Schiff base ligand as a new class of bioactive compounds containing indole core: synthesis and characterization. Int. J. Pharmcy and Pharm. Sci, 8, (1): 197-204, (2016)" }, { "key": "ref21", "doi": "10.13005/ojc/340147", "unstructured": "Waddai, F.Y., Karim, E. K.,Hussen, S. A., Synthesis, spectral characterization and antimicrobial activity of some transition metal complexes with new Schiff base ligand. Oriental Journal of Chemistry. Vol. 34 No. 1, (2018)" }, { "key": "ref22", "doi": "10.14233/ajchem.2018.21212", "unstructured": "Palanimurugan, A. Kulandaisamy, A. Synthesis and biological activities of 14- membered macrocyclic Schiff base metal complexes. Asian Journal of Chemistry, Vol. 30, No. (6): 1262-1268, (2018)" }, { "key": "ref23", "doi": "10.21203/rs.3.rs-2303936/v1", "unstructured": "Arumugam, A.P., Guhanathan, S. Elango, G. Co(II), Ni(II) and Cu(II) complexes with Schiff base ligand synthesis characterization antimicrobial molecular docking studies. (2017)" }, { "key": "ref24", "doi": "10.2298/jsc090408009m", "unstructured": "Munde, A., Jagdale A., Jadhav, S., Chondhekar, T. Synthesis, characterization and thermal study of some transition metal complexes of an asymmetrical tetradentate Schiff base ligand. J. Serb. Chem. Soc.75, (3): 349-359, (2010)" }, { "key": "ref25", "unstructured": "Patil, A., Donde, K., Raut S. Synthesis, characterization and biological activity of mixed ligand Co(II) complexes of Schiff base 2-amino-4-nitrophenol-n-salicylidene with some amino acids. Journal of Chemical and Pharmaceutical Research, 4: 1413-1425. (2012)" }, { "key": "ref26", "doi": "10.2298/jsc100607034s", "unstructured": "Singh, D. P., Grover, V., Jain, K. Synthesis and characterization of divalent metal complexes of the macrocyclic ligand derived from istin and 1,2 diaminobenzene, Journal of the Serbian Chemical Society.76(3), 385-393, ( 2011)" }, { "key": "ref27", "unstructured": "Nakamoto, K. Infrared Spectra of Inorganic and Coordination Spectroscopy, 1stEdn., Elsever, Amesterdam,. (1968)" }, { "key": "ref28", "unstructured": "Nakamoto, K.. Infrared Spectra of Inorganic and Coordination Compounds, Wiley Interscience, New York, (1970)" }, { "key": "ref29", "unstructured": "Goel, V. Malhotra, S. R. Macrocyclic Schiff base complexes-preparation, characterization and biological activity. Der Pharma. Chemica, 9, (2): 60–66, (2017)" }, { "key": "ref30", "unstructured": "Panchbhai, M. A., Bhave, N. S., Synthesis and characterization Cobalt(II), Nickel(II) and Copper(II) complexes of 14-membered macrocyclic ligand. Asian Journal of Chemistry, Vol. 21, No.(8): 6057-6067, (2009)" }, { "key": "ref31", "unstructured": "Sakhare, M.A., Dhokte, A.O., Bagal, M.R., Arbad, B. R. Spectral and antimicrobial studies on Nd(III), Sm(III) and Gd(III) complexes with a tetraaza macrocyclic ligand, American Int. Journal of Research in Formal, Applied and Natural Sciences, 47-52, (2013)" } ], "record": { "registrant": "Longman Publishers", "registered": "2024-02-16", "updated": "2026-09-17", "issue_number": 1, "source": "crossref-api", "source_agency": "Crossref (member 25296)" } }, "url_after": "https://www.jst.org.in/index.php/pub/article/view/592", "sha256_before": null, "sha256_after": "7e9ead2bc0ff860fca155ecf8f2944603565f9bbd802a3326e13edd41f739594" }, { "seq": 2, "kind": "update", "at": "2026-09-29 23:59:41", "by": "Administrator (admin)", "by_kind": "user", "note": "record re-read from api.crossref.org", "changes": [ { "path": "container.titles.0.value", "from": "Journal of Science & Technology", "to": "Journal of Science & Technology" } ], "record_after": { "format": "smartscholars-doi-metadata/1.0", "doi": "10.46243/jst.2022.v7.i01.pp60-68", "referent": "Creation", "type": "JournalArticle", "structural_type": "Digital", "modes": [ "Visual" ], "characters": [ "Language" ], "titles": [ { "value": "Synthesis, Characterization and Antimicrobial Evaluation of a new Macrocyclic Ligand and Its Co (II), Ni (II,) Cu (II) and Zn (II)Complexes", "type": "PrincipalTitle", "lang": "en" } ], "identifiers": [ { "type": "DOI", "value": "10.46243/jst.2022.v7.i01.pp60-68" } ], "agents": [ { "role": "author", "name": { "given": "Sopan A. Najan", "family": "Sopan A. Najan" }, "sequence": "first" }, { "role": "publisher", "name": { "org": "Longman Publishers" } } ], "dates": { "published": "2022-05-22", "date_type": "PublicationDate", "online": "2022-05-22" }, "language": "en", "container": { "type": "Journal", "titles": [ { "value": "Journal of Science & Technology", "type": "PrincipalTitle" } ], "identifiers": [ { "type": "ISSN", "value": "2456-5660", "medium": "electronic" } ], "volume": "7", "issue": "Special 1", "pages": { "first": "60", "last": "68" } }, "links": [ { "url": "https://www.jst.org.in/index.php/pub/article/view/592", "return_type": "text/html", "primary": true }, { "url": "https://www.jst.org.in/index.php/pub/article/download/592/525", "purpose": "text-mining", "return_type": "application/pdf" }, { "url": "https://www.jst.org.in/index.php/pub/article/download/592/2276", "purpose": "text-mining", "return_type": "application/xml" }, { "url": "https://jst.org.in/admin/uploads/Najan.pdf", "purpose": "similarity-checking" } ], "abstract": { "value": "Coordination complexes derived from a new macrocyclic ligand with Co(II), Ni(II), Cu(II), and Zn(II) metal ions were synthesized and characterized. The Schiff base ligand was prepared by the condensation of 1-(5-bromo-2-hydroxyphenyl)-3-(furan-2-yl)propane-1,3-dione with o-phenylenediamine. The synthesized metal complexes were characterized by conductivity, UV–Visible, FTIR, ^1H NMR, TGA-DTA, and XRD analyses. The results indicated that all the complexes are non-electrolytic in nature and exhibit a hexadentate coordination mode through four nitrogen atoms of the azomethine groups. The ligand and its metal complexes were evaluated in vitro for their antibacterial and antifungal activities against selected microorganisms using Gentamycin, Ampicillin, Chloramphenicol, Ciprofloxacin, Norfloxacin, Nystatin, and Griseofulvin as standard drugs. The synthesized complexes demonstrated higher biological activities than the corresponding standard drugs, indicating their potential antimicrobial properties.", "lang": "en" }, "license": { "url": "https://creativecommons.org/licenses/by/4.0/", "start": "2022-05-22", "applies_to": "vor" }, "references": [ { "key": "ref1", "unstructured": "Jayaseelan, P., Prasad, S. Synthesis, spectral characterization, electrochemical and anti-microbial activities" }, { "key": "ref2", "doi": "10.1080/15533174.2016.1186091", "unstructured": "Shakir, M., Bano N., Rauf, A., Kazmi, S. and Alam, M. Synthesis and characterization of pharmacologically active 18-membered tetraamide macrocyclic complexes of Mn(II), Co(II), Ni(II), Cu(II), and Zn(II): In-vitro antimicrobial, anticancer screening, DNA interaction and docking studies Inorg. Nano-Met. Chem. 47, 576, (2017)" }, { "key": "ref3", "doi": "10.2298/jsc090408009m", "unstructured": "Munde, A., Jagdale A., Jadhav, S., Chondhekar, T. 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Soc., 62, N-4, (2017)" }, { "key": "ref9", "doi": "10.1007/s12039-017-1398-8", "unstructured": "Shakir, M., Bano, N., Rauf, M., and Owais, MPharmacologically significant tetraaza macrocyclic metalcomplexes derived from isatin and 3,4-diaminobenzophenone: Synthesis, spectral studies and comparative in vitro biological assessment J. Chem. Sci. Vol. 129, No. 12,, pp. 1905–1920, (2017). Published by: Longman Publishers www.jst.org.in P age 66 | 9" }, { "key": "ref10", "unstructured": "Mishra, R. M., Pandey, S., Saxena, R. “Homozygous hemoglobin D with alpha thalassemia: case report,” The Open Hematology Journal, Vol. (2): 1–4, (2011)" }, { "key": "ref11", "doi": "10.22214/ijraset.2019.1103", "unstructured": "Lawrence, K. Leo, Angelo, A.N. Paul. Synthesis, characterization and antibacterial activity of chiral 1, 1’ – (4, 6–dihydroxy–1, 3-phenylene) bisethanone based tetraaza macrocyclic Co (II), Ni (II), Cu (II) and Zn (II) metal complexes. 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Spectroscopy of Organic Compounds, New Age International (P) Ltd., New Delhi, India, (1999)" }, { "key": "ref19", "doi": "10.31788/rjc.2018.1123033", "unstructured": "Vijayalakshmi, M., Synthesis and spectral characterization of Schiff base transition metal complexes, DNA cleavage and antibacterial activity studies,Rasayan J. of Chem. 11, (2): 857–864, (2018)" }, { "key": "ref20", "unstructured": "Gunvanthrao, N. Hire, B. Mruthyunjayaswamy, M. Metal (II) complexes of ONO donor Schiff base ligand as a new class of bioactive compounds containing indole core: synthesis and characterization. Int. J. Pharmcy and Pharm. Sci, 8, (1): 197-204, (2016)" }, { "key": "ref21", "doi": "10.13005/ojc/340147", "unstructured": "Waddai, F.Y., Karim, E. K.,Hussen, S. A., Synthesis, spectral characterization and antimicrobial activity of some transition metal complexes with new Schiff base ligand. Oriental Journal of Chemistry. Vol. 34 No. 1, (2018)" }, { "key": "ref22", "doi": "10.14233/ajchem.2018.21212", "unstructured": "Palanimurugan, A. Kulandaisamy, A. Synthesis and biological activities of 14- membered macrocyclic Schiff base metal complexes. Asian Journal of Chemistry, Vol. 30, No. (6): 1262-1268, (2018)" }, { "key": "ref23", "doi": "10.21203/rs.3.rs-2303936/v1", "unstructured": "Arumugam, A.P., Guhanathan, S. Elango, G. Co(II), Ni(II) and Cu(II) complexes with Schiff base ligand synthesis characterization antimicrobial molecular docking studies. (2017)" }, { "key": "ref24", "doi": "10.2298/jsc090408009m", "unstructured": "Munde, A., Jagdale A., Jadhav, S., Chondhekar, T. Synthesis, characterization and thermal study of some transition metal complexes of an asymmetrical tetradentate Schiff base ligand. J. Serb. Chem. Soc.75, (3): 349-359, (2010)" }, { "key": "ref25", "unstructured": "Patil, A., Donde, K., Raut S. Synthesis, characterization and biological activity of mixed ligand Co(II) complexes of Schiff base 2-amino-4-nitrophenol-n-salicylidene with some amino acids. Journal of Chemical and Pharmaceutical Research, 4: 1413-1425. (2012)" }, { "key": "ref26", "doi": "10.2298/jsc100607034s", "unstructured": "Singh, D. P., Grover, V., Jain, K. Synthesis and characterization of divalent metal complexes of the macrocyclic ligand derived from istin and 1,2 diaminobenzene, Journal of the Serbian Chemical Society.76(3), 385-393, ( 2011)" }, { "key": "ref27", "unstructured": "Nakamoto, K. Infrared Spectra of Inorganic and Coordination Spectroscopy, 1stEdn., Elsever, Amesterdam,. (1968)" }, { "key": "ref28", "unstructured": "Nakamoto, K.. Infrared Spectra of Inorganic and Coordination Compounds, Wiley Interscience, New York, (1970)" }, { "key": "ref29", "unstructured": "Goel, V. Malhotra, S. R. Macrocyclic Schiff base complexes-preparation, characterization and biological activity. Der Pharma. Chemica, 9, (2): 60–66, (2017)" }, { "key": "ref30", "unstructured": "Panchbhai, M. A., Bhave, N. S., Synthesis and characterization Cobalt(II), Nickel(II) and Copper(II) complexes of 14-membered macrocyclic ligand. Asian Journal of Chemistry, Vol. 21, No.(8): 6057-6067, (2009)" }, { "key": "ref31", "unstructured": "Sakhare, M.A., Dhokte, A.O., Bagal, M.R., Arbad, B. R. Spectral and antimicrobial studies on Nd(III), Sm(III) and Gd(III) complexes with a tetraaza macrocyclic ligand, American Int. Journal of Research in Formal, Applied and Natural Sciences, 47-52, (2013)" } ], "record": { "registrant": "Longman Publishers", "registered": "2024-02-16", "updated": "2026-09-17", "issue_number": 1, "source": "crossref-api", "source_agency": "Crossref (member 25296)" } }, "url_after": "https://www.jst.org.in/index.php/pub/article/view/592", "sha256_before": "7e9ead2bc0ff860fca155ecf8f2944603565f9bbd802a3326e13edd41f739594", "sha256_after": "a122aa31d6afd4989da8afc048364e0f944ddf26269f4018d54ec11549a11d7b" } ] }