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Mitragynaparvifolia is one of the medicinal plants considered for repurposing in the management of covid -19 because i t is crucially significant as it contains rich fraction of alkaloids. 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Korth (Rubiaseae): An endangered tree of pharmaceutical importance, 22 June 2020" }, { "path": "references.11.key", "from": null, "to": "ref12" }, { "path": "references.11.unstructured", "from": null, "to": "Fang Gong–Hai–peng Gu, Qi-tai-Xu, Wen–yi. Kang. Genus Mitragyna :Ethanomedicinal uses and pharmacological studies. Phytopharmacology 3 (2), 263-272, 2012" }, { "path": "references.12.key", "from": null, "to": "ref13" }, { "path": "references.12.unstructured", "from": null, "to": "Kunte, Krushnamegh. Butterflies of Peninsular India. India, A Lifescape. Hyderabad, India: Universities Press. p. 224. (2000). ISBN 978-8173713545" }, { "path": "references.13.doi", "from": null, "to": "10.1016/j.jep.2017.03.020" }, { "path": "references.13.key", "from": null, "to": "ref14" }, { "path": "references.13.unstructured", "from": null, "to": "P N Brown, J A Lund, SJ Murch A botanical Phytochemical and ethnomedicinal review of the genus MitragynaKorth–Jorunal of ethnopharmacology, 2017" }, { "path": "references.14.doi", "from": null, "to": "10.31018/jans.v7i2.679" }, { "path": "references.14.key", "from": null, "to": "ref15" }, { "path": "references.14.unstructured", "from": null, "to": "S. Kumar, L. L. Behra, N. S. Patil and D. B. Jadega(Growth and yield of vigna radiate L) under Terminalia arjuna and Mitragynaparvifolia based agrisilviculture system, Journal of applied and natural Science 7 (2): 758-762 (2015)" }, { "path": "references.15.doi", "from": null, "to": "10.1016/j.phytochem.2006.06.017" }, { "path": "references.15.key", "from": null, "to": "ref16" }, { "path": "references.15.unstructured", "from": null, "to": "Richa Panday, Madan M. Gupta. Heteroyohimbinoid type oxindole alkaloids fownmitragynaparrifolia, Phytochemistry Vol.67, issue 19 octomber 2006, Page 2164-2169" }, { "path": "references.16.key", "from": null, "to": "ref17" }, { "path": "references.16.unstructured", "from": null, "to": "Sharda Roy, Vikas Chandra Roy, dr. R. C. Roy, A Review of M.P. (Roxb) Korth: PHARMATUTOR–2013" }, { "path": "references.17.key", "from": null, "to": "ref18" }, { "path": "references.17.unstructured", "from": null, "to": "Ankit Saneja1, Dhirender Kaushik1*, Sukhbir Lal Khokra1, Pawan Kaushik, Chetan Sharma and K.R. Aneja Evaluation of activities of M. P. fruit extract: Journal of Natural product. Volume 2, 49-54. (2009)" }, { "path": "references.18.doi", "from": null, "to": "10.25004/ijpsdr.2009.010102" }, { "path": "references.18.key", "from": null, "to": "ref19" }, { "path": "references.18.unstructured", "from": null, "to": "Kaushik D, KhokraS.. L., Kauship P., Sanjena A, Sharma C, Aneja K. R., Chaudhary B, Koshy S., Study of analgesic and antimicrobial Potential of MitragynaParvifoliaIJPSDR Apr-June, 2009, Vol 1, Issue 1(6-8)" }, { "path": "references.19.key", "from": null, "to": "ref20" }, { "path": "references.19.unstructured", "from": null, "to": "Dhirendar Kaushik, SukhbirlalKhokra, Pawan Kaushik, Ankit Saneja, Divya Arora. Anticonvulsant activity of mitragynaparvifolia leaves extract: (Pharmacologyonline 3, 101-106, 2009)" }, { "path": "references.2.doi", "from": null, "to": "10.1002/bip.20886" }, { "path": "references.2.key", "from": null, "to": "ref3" }, { "path": "references.2.unstructured", "from": null, "to": "Ireland, D. C., Wang, C. K., Wilson, J. A., Gustafson, K. R., Craik, D. J. (2008). Cyclotides as natural anti-HIV agents. Pept. Sci. 90, 51–60. doi: 10.1002/bip.20886" }, { "path": "references.20.key", "from": null, "to": "ref21" }, { "path": "references.20.unstructured", "from": null, "to": "Vishal B. Vadgujar, Sanjay j. Surana. In vitro investigation of anthelmintic activity of P.R.K. : Vishal B. Vadgujar, Sanjay j. Surana, Veternary world 3(7)326, 2010" }, { "path": "references.21.key", "from": null, "to": "ref22" }, { "path": "references.21.unstructured", "from": null, "to": "R. K. Sahu, G. Tatewar, A. Roy and A. K. 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S, Anxiolytic Investigation of anxiolytic effect of M.P. stem Bark extracts an animal model: Journal Article–Der Phwamacia letter 2009, Vol. 1 No. 2 P. P. 172-181" }, { "path": "references.25.key", "from": null, "to": "ref26" }, { "path": "references.25.unstructured", "from": null, "to": "Arindam A Ghatak, ND Bhembre, Anisha A Kamath, Sneha S. Mehta, MR Mendonca AW. Antiproliferative, antioxidant activity and total phenolic content of MitragynaparifoliaKorth Int J Parm Sci 6 (4), 632–637, 2014" }, { "path": "references.26.key", "from": null, "to": "ref27" }, { "path": "references.26.unstructured", "from": null, "to": "A. P. Jain, M. V. Tole, A. Mittal, N. B. Mahire, Antiarthritic and antipyretic activity of MitragyanaParvifolia : January 2009, Pharcocalogyonline 2:739–749" }, { "path": "references.27.key", "from": null, "to": "ref28" }, { "path": "references.27.unstructured", "from": null, "to": "Amit Gupta and Sushma R. ChaphalkarImmunosupressive and cytotoxic potential of flavanoids form Mitragynaparvifolia, Magnifera Indica and Argle Marmelosa" }, { "path": "references.28.key", "from": null, "to": "ref29" }, { "path": "references.28.unstructured", "from": null, "to": "Ghosh Rimi, Murali Anita, Gowri R. Evaluation of anti-Hypertensive activity of Mitragynaparvifolia (Rox B) Korth root extract and its vasorelaxation potential on calcium chloride induced contraction in asolated rat Aorta: JOURNAL OF DENTAL AND OROFACIAL RESEARCH 14 (1) pp : 28-34, Published : Jan 2018-2019" }, { "path": "references.29.doi", "from": null, "to": "10.30799/jnst.133.18040415" }, { "path": "references.29.key", "from": null, "to": "ref30" }, { "path": "references.29.unstructured", "from": null, "to": "Shailesh C. Kotval, Tessy John, Kokila A Parmar. Green synthesis of copper nanoparticles using mitragynaparvifolia plant bark extract and it’s a antimicrobial study, Journal of Nanoscience and technology" }, { "path": "references.3.doi", "from": null, "to": "10.2174/1381612821666151002113426" }, { "path": "references.3.key", "from": null, "to": "ref4" }, { "path": "references.3.unstructured", "from": null, "to": "Sencanski, M., Radosevic, D., Perovic, V., Gemovic, B., Stanojevic, M., Veljkovic, N., et al. (2015). Natural products as promising therapeutics for treatment of influenza disease. Curr. Pharm. Design 21, 5573–5588. doi: 10.2174/1381612821666151002113426" }, { "path": "references.30.key", "from": null, "to": "ref31" }, { "path": "references.30.unstructured", "from": null, "to": "Anjana Goel, Rashmi Singh, Sandee Kumar Dash, Deepti Gupta. Antiviral activity of few selected indigenous plants against bovine herpes virus-1,Dihydro 16-17, June 2011" }, { "path": "references.31.doi", "from": null, "to": "10.1016/j.ejps.2012.07.012" }, { "path": "references.31.key", "from": null, "to": "ref32" }, { "path": "references.31.unstructured", "from": null, "to": "Ashutosh Shukla et at. b–hydroxyl isomitraphylline alkaloid as an inhibitor of DPP–IV, and its effect on incretin harmone and β–cell proliferation in diabetic rat :Eur Pharm Sci.2012 National Library of medicine. Published by: Longman Publishers www.jst.org.in P a g e 59 | 7" }, { "path": "references.32.key", "from": null, "to": "ref33" }, { "path": "references.32.unstructured", "from": null, "to": "K PashupatVasmatkar, Ashutosh Dubey, Bhawna Tyagi, Pratibha Baral, Shishir Tondon, Amar MS analysis of methanolic extract from stem back & leaves of M.P. (r)" }, { "path": "references.33.doi", "from": null, "to": "10.52816/jdvat.2021.1103" }, { "path": "references.33.key", "from": null, "to": "ref34" }, { "path": "references.33.unstructured", "from": null, "to": "R.Padmavati, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF MITAGYNA PARVIFOLIA LEAF EXTRACTS IN EXPERIMENTAL RATS; Journal of Drug vigilance and alternative therapies, January 2021, DOl : 10.528161/JDVAT 2021.1103" }, { "path": "references.4.doi", "from": null, "to": "10.4103/0973-7847.162110" }, { "path": "references.4.key", "from": null, "to": "ref5" }, { "path": "references.4.unstructured", "from": null, "to": "Alka Dwevedi, Kudeep Sharma and Yogesh K. Sharma, Miraculous tree having enormous Pharmacological implication:Pharmacognosy Rev-2015, July. Dec. 9 (18) 107-113" }, { "path": "references.5.key", "from": null, "to": "ref6" }, { "path": "references.5.unstructured", "from": null, "to": "Brijesh Kumar, Satya Prakash Chaudhary, Anil Kumar Singh KadambaIn Ayurveda-A Critical Review International Journal of Pharmaceutical Archive- 4 (9), Sept. – 2015" }, { "path": "references.6.key", "from": null, "to": "ref7" }, { "path": "references.6.unstructured", "from": null, "to": "Gajendra Pratap Choudhary, Ashutosh Pal Jain. A Review on Mitragynaparvifolia (Roxb.) Korth. - An Indian Medicinal Plant. Ijppr.Human, 2016; Vol. 7 (1): 175-184" }, { "path": "references.7.key", "from": null, "to": "ref8" }, { "path": "references.7.unstructured", "from": null, "to": "Phalak, Paresh Prashant. \"Gifting Trees...: The True Kadam!\". Gifting Trees... Retrieved 2020-05-05. http://en.m.wikipedia.org>wiki. https: //WWW.Stuartxchange.org.>kaim https: //India biodiversity. org>show http://www.flowersindia.net>catlog>slides>kaim, Identification Navendu Page, Vaibhav, Nadan, Kalbag" }, { "path": "references.8.key", "from": null, "to": "ref9" }, { "path": "references.8.unstructured", "from": null, "to": "J. K. Maheshwari, Ethanobotany and medicinal plants of Indian subcontinent book, page 270, 2019" }, { "path": "references.9.key", "from": null, "to": "ref10" }, { "path": "references.9.unstructured", "from": null, "to": "Vinoth Thomas and Yash Dave. Structure and Necrosis of stipular collectors in MitragynaParvifolia (Rubiaceae), Belgian Journal of Botany, Vol. 123, (1990)" }, { "path": "referent", "from": null, "to": "Creation" }, { "path": "structural_type", "from": null, "to": "Digital" }, { "path": "titles.0.lang", "from": null, "to": "en" }, { "path": "titles.0.type", "from": null, "to": "PrincipalTitle" }, { "path": "titles.0.value", "from": null, "to": "A Review of MitragynaParvifolia (Roxb) Korth An Important Medicinal Plant" }, { "path": "type", "from": null, "to": "JournalArticle" } ], "record_after": { "format": "smartscholars-doi-metadata/1.0", "doi": "10.46243/jst.2022.v7.i01.pp53-59", "referent": "Creation", "type": "JournalArticle", "structural_type": "Digital", "modes": [ "Visual" ], "characters": [ "Language" ], "titles": [ { "value": "A Review of MitragynaParvifolia (Roxb) Korth An Important Medicinal Plant", "type": "PrincipalTitle", "lang": "en" } ], "identifiers": [ { "type": "DOI", "value": "10.46243/jst.2022.v7.i01.pp53-59" } ], "agents": [ { "role": "author", "name": { "given": "Usha Jadhav", "family": "Usha Jadhav" }, "sequence": "first" }, { "role": "publisher", "name": { "org": "Longman Publishers" } } ], "dates": { "published": "2022-05-22", "date_type": "PublicationDate", "online": "2022-05-22" }, "language": "en", "container": { "type": "Journal", "titles": [ { "value": "Journal of Science & Technology", "type": "PrincipalTitle" } ], "identifiers": [ { "type": "ISSN", "value": "2456-5660", "medium": "electronic" } ], "volume": "7", "issue": "Special 1", "pages": { "first": "53", "last": "59" } }, "links": [ { "url": "https://www.jst.org.in/index.php/pub/article/view/591", "return_type": "text/html", "primary": true }, { "url": "https://www.jst.org.in/index.php/pub/article/download/591/524", "purpose": "text-mining", "return_type": "application/pdf" }, { "url": "https://www.jst.org.in/index.php/pub/article/download/591/2279", "purpose": "text-mining", "return_type": "application/xml" }, { "url": "https://jst.org.in/admin/uploads/Misal.pdf", "purpose": "similarity-checking" } ], "abstract": { "value": "Herbal plants are potent in curing various diseases form common cold to dreaded diseases like variety at cancers as they have comparatively lesser side effects than synthetic drugs. Corona -virus 2019 (COVID -19) pandemic has identified and experimented many drugs in its management and these agents included both new and old drugs. MitragranaParv ifolia (Roxb.) korthpopularily known as kaim, is a deciduous traditional medicinal plant belongs to genus Rubiaceae. It is a true kadamba. Mitragynaparvifolia is one of the medicinal plants considered for repurposing in the management of covid -19 because i t is crucially significant as it contains rich fraction of alkaloids. Mitragynaparvifolia is crucially significant as it has largest number of phytohemicals (such as alkaloids, flavanoids, tannins, glycosides, carbohydrates, phenols, aldehydes, ketones, ph ytosterols, triterpenes, triterpenoids, saponins, indole alkaloids etc.) and Secondary metabolites (viz.quinolic acid, quinovic acid, β -sitosterol, methyl acetate, pyroligenous acid, scopoletine, therophylline, daucosterol, cadambagenic acid, cadamine, cad ambine, isocadambine, isodihydrocadamabine etc.) In Ayuveda medicinal effect of kadamba is described in different sunhitas like Charak Samhita, Sushrutasamhita, Ashtanga hridya, Haritsamhita, Chakardatta etc. Kadamba is used as antihepatotoxic, antibacteri al, antimalarial, antimicrobial, analgesic, anti -inflammatory, antipyretic, anti - oxidant wound healing activities, diuretic and laxative. Antiarthritic, Anticonvulsant, Anthelmintic, antinociceptive, Antiproliferative activity. MitragynaParvifolia plant extract also possess Antifungal, Antidiarrheal, Antiviral activity leads to the development of potent antiviral drug, which can be safer, cost effective and can be used in the Medical filed in promoting rural development and prosperity", "lang": "en" }, "license": { "url": "https://creativecommons.org/licenses/by/4.0/", "start": "2022-05-22", "applies_to": "vor" }, "references": [ { "key": "ref1", "unstructured": "Gupta V, Kumar P, Bansal P, Singh R. Anti-inflammatory and Anti-nociceptive Activity of Mitragynaparvifolia, Asian J of Med Sci 2009; 1 (3): 97-99. Published by: Longman Publishers www.jst.org.in P a g e 58 | 7" }, { "key": "ref2", "doi": "10.1046/j.1365-2672.2003.02026.x", "unstructured": "Jassim, S. A., Naji, M. A. (2003). Novel antiviral agents: a medicinal plant perspective. J. Appl. Microbiol. 95, 412–427. doi:10.1046/j.1365-2672.2003. 02026.x" }, { "key": "ref3", "doi": "10.1002/bip.20886", "unstructured": "Ireland, D. C., Wang, C. K., Wilson, J. A., Gustafson, K. R., Craik, D. J. (2008). Cyclotides as natural anti-HIV agents. Pept. Sci. 90, 51–60. doi: 10.1002/bip.20886" }, { "key": "ref4", "doi": "10.2174/1381612821666151002113426", "unstructured": "Sencanski, M., Radosevic, D., Perovic, V., Gemovic, B., Stanojevic, M., Veljkovic, N., et al. (2015). Natural products as promising therapeutics for treatment of influenza disease. Curr. Pharm. Design 21, 5573–5588. doi: 10.2174/1381612821666151002113426" }, { "key": "ref5", "doi": "10.4103/0973-7847.162110", "unstructured": "Alka Dwevedi, Kudeep Sharma and Yogesh K. Sharma, Miraculous tree having enormous Pharmacological implication:Pharmacognosy Rev-2015, July. Dec. 9 (18) 107-113" }, { "key": "ref6", "unstructured": "Brijesh Kumar, Satya Prakash Chaudhary, Anil Kumar Singh KadambaIn Ayurveda-A Critical Review International Journal of Pharmaceutical Archive- 4 (9), Sept. – 2015" }, { "key": "ref7", "unstructured": "Gajendra Pratap Choudhary, Ashutosh Pal Jain. A Review on Mitragynaparvifolia (Roxb.) Korth. - An Indian Medicinal Plant. Ijppr.Human, 2016; Vol. 7 (1): 175-184" }, { "key": "ref8", "unstructured": "Phalak, Paresh Prashant. \"Gifting Trees...: The True Kadam!\". Gifting Trees... Retrieved 2020-05-05. http://en.m.wikipedia.org>wiki. https: //WWW.Stuartxchange.org.>kaim https: //India biodiversity. org>show http://www.flowersindia.net>catlog>slides>kaim, Identification Navendu Page, Vaibhav, Nadan, Kalbag" }, { "key": "ref9", "unstructured": "J. K. Maheshwari, Ethanobotany and medicinal plants of Indian subcontinent book, page 270, 2019" }, { "key": "ref10", "unstructured": "Vinoth Thomas and Yash Dave. Structure and Necrosis of stipular collectors in MitragynaParvifolia (Rubiaceae), Belgian Journal of Botany, Vol. 123, (1990)" }, { "key": "ref11", "doi": "10.1007/s11627-020-10089-6", "unstructured": "Ashok Kumar Patel, Deepika Lodha&Nerpat S. Shekhawat. An improved micropropagation protocol for ex-situ conversation of Mitragynaparvifolia (Roxb.) Korth (Rubiaseae): An endangered tree of pharmaceutical importance, 22 June 2020" }, { "key": "ref12", "unstructured": "Fang Gong–Hai–peng Gu, Qi-tai-Xu, Wen–yi. Kang. Genus Mitragyna :Ethanomedicinal uses and pharmacological studies. Phytopharmacology 3 (2), 263-272, 2012" }, { "key": "ref13", "unstructured": "Kunte, Krushnamegh. Butterflies of Peninsular India. India, A Lifescape. Hyderabad, India: Universities Press. p. 224. (2000). ISBN 978-8173713545" }, { "key": "ref14", "doi": "10.1016/j.jep.2017.03.020", "unstructured": "P N Brown, J A Lund, SJ Murch A botanical Phytochemical and ethnomedicinal review of the genus MitragynaKorth–Jorunal of ethnopharmacology, 2017" }, { "key": "ref15", "doi": "10.31018/jans.v7i2.679", "unstructured": "S. Kumar, L. L. Behra, N. S. Patil and D. B. Jadega(Growth and yield of vigna radiate L) under Terminalia arjuna and Mitragynaparvifolia based agrisilviculture system, Journal of applied and natural Science 7 (2): 758-762 (2015)" }, { "key": "ref16", "doi": "10.1016/j.phytochem.2006.06.017", "unstructured": "Richa Panday, Madan M. Gupta. Heteroyohimbinoid type oxindole alkaloids fownmitragynaparrifolia, Phytochemistry Vol.67, issue 19 octomber 2006, Page 2164-2169" }, { "key": "ref17", "unstructured": "Sharda Roy, Vikas Chandra Roy, dr. R. C. Roy, A Review of M.P. (Roxb) Korth: PHARMATUTOR–2013" }, { "key": "ref18", "unstructured": "Ankit Saneja1, Dhirender Kaushik1*, Sukhbir Lal Khokra1, Pawan Kaushik, Chetan Sharma and K.R. Aneja Evaluation of activities of M. P. fruit extract: Journal of Natural product. Volume 2, 49-54. (2009)" }, { "key": "ref19", "doi": "10.25004/ijpsdr.2009.010102", "unstructured": "Kaushik D, KhokraS.. L., Kauship P., Sanjena A, Sharma C, Aneja K. R., Chaudhary B, Koshy S., Study of analgesic and antimicrobial Potential of MitragynaParvifoliaIJPSDR Apr-June, 2009, Vol 1, Issue 1(6-8)" }, { "key": "ref20", "unstructured": "Dhirendar Kaushik, SukhbirlalKhokra, Pawan Kaushik, Ankit Saneja, Divya Arora. Anticonvulsant activity of mitragynaparvifolia leaves extract: (Pharmacologyonline 3, 101-106, 2009)" }, { "key": "ref21", "unstructured": "Vishal B. Vadgujar, Sanjay j. Surana. In vitro investigation of anthelmintic activity of P.R.K. : Vishal B. Vadgujar, Sanjay j. Surana, Veternary world 3(7)326, 2010" }, { "key": "ref22", "unstructured": "R. K. Sahu, G. Tatewar, A. Roy and A. K. Jha ANTHEMINTIC ACTIVITY OF MITROGYNA PARVIFOLIA (ROXB) KORTH FRUIT EXTRACT : World Journal of Pharmacy & Pharmaceutical Science 6 (12) 1349-1354, 2017" }, { "key": "ref23", "unstructured": "Vikas Gupta, Pawan Kumar, Parveen Bansal, Ranjeet Singh Antinflammatory and antinociceptive activity of MitragynaParvifolia:" }, { "key": "ref24", "unstructured": "Pundir Ram Kumar, Bishnoi Shreya, Antimicrobial activity of mitragynaparvifolia barks and Butea monosperma leaves extract against human pathogenic microbial strain.: International Journal of Drug Development and research 3(4) 0-0, 2011" }, { "key": "ref25", "unstructured": "Vishal B. B., Sanjay J. S, Anxiolytic Investigation of anxiolytic effect of M.P. stem Bark extracts an animal model: Journal Article–Der Phwamacia letter 2009, Vol. 1 No. 2 P. P. 172-181" }, { "key": "ref26", "unstructured": "Arindam A Ghatak, ND Bhembre, Anisha A Kamath, Sneha S. Mehta, MR Mendonca AW. Antiproliferative, antioxidant activity and total phenolic content of MitragynaparifoliaKorth Int J Parm Sci 6 (4), 632–637, 2014" }, { "key": "ref27", "unstructured": "A. P. Jain, M. V. Tole, A. Mittal, N. B. Mahire, Antiarthritic and antipyretic activity of MitragyanaParvifolia : January 2009, Pharcocalogyonline 2:739–749" }, { "key": "ref28", "unstructured": "Amit Gupta and Sushma R. ChaphalkarImmunosupressive and cytotoxic potential of flavanoids form Mitragynaparvifolia, Magnifera Indica and Argle Marmelosa" }, { "key": "ref29", "unstructured": "Ghosh Rimi, Murali Anita, Gowri R. Evaluation of anti-Hypertensive activity of Mitragynaparvifolia (Rox B) Korth root extract and its vasorelaxation potential on calcium chloride induced contraction in asolated rat Aorta: JOURNAL OF DENTAL AND OROFACIAL RESEARCH 14 (1) pp : 28-34, Published : Jan 2018-2019" }, { "key": "ref30", "doi": "10.30799/jnst.133.18040415", "unstructured": "Shailesh C. Kotval, Tessy John, Kokila A Parmar. Green synthesis of copper nanoparticles using mitragynaparvifolia plant bark extract and it’s a antimicrobial study, Journal of Nanoscience and technology" }, { "key": "ref31", "unstructured": "Anjana Goel, Rashmi Singh, Sandee Kumar Dash, Deepti Gupta. Antiviral activity of few selected indigenous plants against bovine herpes virus-1,Dihydro 16-17, June 2011" }, { "key": "ref32", "doi": "10.1016/j.ejps.2012.07.012", "unstructured": "Ashutosh Shukla et at. b–hydroxyl isomitraphylline alkaloid as an inhibitor of DPP–IV, and its effect on incretin harmone and β–cell proliferation in diabetic rat :Eur Pharm Sci.2012 National Library of medicine. Published by: Longman Publishers www.jst.org.in P a g e 59 | 7" }, { "key": "ref33", "unstructured": "K PashupatVasmatkar, Ashutosh Dubey, Bhawna Tyagi, Pratibha Baral, Shishir Tondon, Amar MS analysis of methanolic extract from stem back & leaves of M.P. (r)" }, { "key": "ref34", "doi": "10.52816/jdvat.2021.1103", "unstructured": "R.Padmavati, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF MITAGYNA PARVIFOLIA LEAF EXTRACTS IN EXPERIMENTAL RATS; Journal of Drug vigilance and alternative therapies, January 2021, DOl : 10.528161/JDVAT 2021.1103" } ], "record": { "registrant": "Longman Publishers", "registered": "2024-02-16", "updated": "2026-09-17", "issue_number": 1, "source": "crossref-api", "source_agency": "Crossref (member 25296)" } }, "url_after": "https://www.jst.org.in/index.php/pub/article/view/591", "sha256_before": null, "sha256_after": "f6738e45e7a05578f6161dc081345f4b2899fae24fbbd75affb5de69f1287bf2" }, { "seq": 2, "kind": "update", "at": "2026-09-29 23:59:41", "by": "Administrator (admin)", "by_kind": "user", "note": "record re-read from api.crossref.org", "changes": [ { "path": "container.titles.0.value", "from": "Journal of Science & Technology", "to": "Journal of Science & Technology" } ], "record_after": { "format": "smartscholars-doi-metadata/1.0", "doi": "10.46243/jst.2022.v7.i01.pp53-59", "referent": "Creation", "type": "JournalArticle", "structural_type": "Digital", "modes": [ "Visual" ], "characters": [ "Language" ], "titles": [ { "value": "A Review of MitragynaParvifolia (Roxb) Korth An Important Medicinal Plant", "type": "PrincipalTitle", "lang": "en" } ], "identifiers": [ { "type": "DOI", "value": "10.46243/jst.2022.v7.i01.pp53-59" } ], "agents": [ { "role": "author", "name": { "given": "Usha Jadhav", "family": "Usha Jadhav" }, "sequence": "first" }, { "role": "publisher", "name": { "org": "Longman Publishers" } } ], "dates": { "published": "2022-05-22", "date_type": "PublicationDate", "online": "2022-05-22" }, "language": "en", "container": { "type": "Journal", "titles": [ { "value": "Journal of Science & Technology", "type": "PrincipalTitle" } ], "identifiers": [ { "type": "ISSN", "value": "2456-5660", "medium": "electronic" } ], "volume": "7", "issue": "Special 1", "pages": { "first": "53", "last": "59" } }, "links": [ { "url": "https://www.jst.org.in/index.php/pub/article/view/591", "return_type": "text/html", "primary": true }, { "url": "https://www.jst.org.in/index.php/pub/article/download/591/524", "purpose": "text-mining", "return_type": "application/pdf" }, { "url": "https://www.jst.org.in/index.php/pub/article/download/591/2279", "purpose": "text-mining", "return_type": "application/xml" }, { "url": "https://jst.org.in/admin/uploads/Misal.pdf", "purpose": "similarity-checking" } ], "abstract": { "value": "Herbal plants are potent in curing various diseases form common cold to dreaded diseases like variety at cancers as they have comparatively lesser side effects than synthetic drugs. Corona -virus 2019 (COVID -19) pandemic has identified and experimented many drugs in its management and these agents included both new and old drugs. MitragranaParv ifolia (Roxb.) korthpopularily known as kaim, is a deciduous traditional medicinal plant belongs to genus Rubiaceae. It is a true kadamba. Mitragynaparvifolia is one of the medicinal plants considered for repurposing in the management of covid -19 because i t is crucially significant as it contains rich fraction of alkaloids. Mitragynaparvifolia is crucially significant as it has largest number of phytohemicals (such as alkaloids, flavanoids, tannins, glycosides, carbohydrates, phenols, aldehydes, ketones, ph ytosterols, triterpenes, triterpenoids, saponins, indole alkaloids etc.) and Secondary metabolites (viz.quinolic acid, quinovic acid, β -sitosterol, methyl acetate, pyroligenous acid, scopoletine, therophylline, daucosterol, cadambagenic acid, cadamine, cad ambine, isocadambine, isodihydrocadamabine etc.) In Ayuveda medicinal effect of kadamba is described in different sunhitas like Charak Samhita, Sushrutasamhita, Ashtanga hridya, Haritsamhita, Chakardatta etc. Kadamba is used as antihepatotoxic, antibacteri al, antimalarial, antimicrobial, analgesic, anti -inflammatory, antipyretic, anti - oxidant wound healing activities, diuretic and laxative. Antiarthritic, Anticonvulsant, Anthelmintic, antinociceptive, Antiproliferative activity. MitragynaParvifolia plant extract also possess Antifungal, Antidiarrheal, Antiviral activity leads to the development of potent antiviral drug, which can be safer, cost effective and can be used in the Medical filed in promoting rural development and prosperity", "lang": "en" }, "license": { "url": "https://creativecommons.org/licenses/by/4.0/", "start": "2022-05-22", "applies_to": "vor" }, "references": [ { "key": "ref1", "unstructured": "Gupta V, Kumar P, Bansal P, Singh R. Anti-inflammatory and Anti-nociceptive Activity of Mitragynaparvifolia, Asian J of Med Sci 2009; 1 (3): 97-99. Published by: Longman Publishers www.jst.org.in P a g e 58 | 7" }, { "key": "ref2", "doi": "10.1046/j.1365-2672.2003.02026.x", "unstructured": "Jassim, S. A., Naji, M. A. (2003). Novel antiviral agents: a medicinal plant perspective. J. Appl. Microbiol. 95, 412–427. doi:10.1046/j.1365-2672.2003. 02026.x" }, { "key": "ref3", "doi": "10.1002/bip.20886", "unstructured": "Ireland, D. C., Wang, C. K., Wilson, J. A., Gustafson, K. R., Craik, D. J. (2008). Cyclotides as natural anti-HIV agents. Pept. Sci. 90, 51–60. doi: 10.1002/bip.20886" }, { "key": "ref4", "doi": "10.2174/1381612821666151002113426", "unstructured": "Sencanski, M., Radosevic, D., Perovic, V., Gemovic, B., Stanojevic, M., Veljkovic, N., et al. (2015). Natural products as promising therapeutics for treatment of influenza disease. Curr. Pharm. Design 21, 5573–5588. doi: 10.2174/1381612821666151002113426" }, { "key": "ref5", "doi": "10.4103/0973-7847.162110", "unstructured": "Alka Dwevedi, Kudeep Sharma and Yogesh K. Sharma, Miraculous tree having enormous Pharmacological implication:Pharmacognosy Rev-2015, July. Dec. 9 (18) 107-113" }, { "key": "ref6", "unstructured": "Brijesh Kumar, Satya Prakash Chaudhary, Anil Kumar Singh KadambaIn Ayurveda-A Critical Review International Journal of Pharmaceutical Archive- 4 (9), Sept. – 2015" }, { "key": "ref7", "unstructured": "Gajendra Pratap Choudhary, Ashutosh Pal Jain. A Review on Mitragynaparvifolia (Roxb.) Korth. - An Indian Medicinal Plant. Ijppr.Human, 2016; Vol. 7 (1): 175-184" }, { "key": "ref8", "unstructured": "Phalak, Paresh Prashant. \"Gifting Trees...: The True Kadam!\". Gifting Trees... Retrieved 2020-05-05. http://en.m.wikipedia.org>wiki. https: //WWW.Stuartxchange.org.>kaim https: //India biodiversity. org>show http://www.flowersindia.net>catlog>slides>kaim, Identification Navendu Page, Vaibhav, Nadan, Kalbag" }, { "key": "ref9", "unstructured": "J. K. Maheshwari, Ethanobotany and medicinal plants of Indian subcontinent book, page 270, 2019" }, { "key": "ref10", "unstructured": "Vinoth Thomas and Yash Dave. Structure and Necrosis of stipular collectors in MitragynaParvifolia (Rubiaceae), Belgian Journal of Botany, Vol. 123, (1990)" }, { "key": "ref11", "doi": "10.1007/s11627-020-10089-6", "unstructured": "Ashok Kumar Patel, Deepika Lodha&Nerpat S. Shekhawat. An improved micropropagation protocol for ex-situ conversation of Mitragynaparvifolia (Roxb.) Korth (Rubiaseae): An endangered tree of pharmaceutical importance, 22 June 2020" }, { "key": "ref12", "unstructured": "Fang Gong–Hai–peng Gu, Qi-tai-Xu, Wen–yi. Kang. Genus Mitragyna :Ethanomedicinal uses and pharmacological studies. Phytopharmacology 3 (2), 263-272, 2012" }, { "key": "ref13", "unstructured": "Kunte, Krushnamegh. Butterflies of Peninsular India. India, A Lifescape. Hyderabad, India: Universities Press. p. 224. (2000). ISBN 978-8173713545" }, { "key": "ref14", "doi": "10.1016/j.jep.2017.03.020", "unstructured": "P N Brown, J A Lund, SJ Murch A botanical Phytochemical and ethnomedicinal review of the genus MitragynaKorth–Jorunal of ethnopharmacology, 2017" }, { "key": "ref15", "doi": "10.31018/jans.v7i2.679", "unstructured": "S. Kumar, L. L. Behra, N. S. Patil and D. B. Jadega(Growth and yield of vigna radiate L) under Terminalia arjuna and Mitragynaparvifolia based agrisilviculture system, Journal of applied and natural Science 7 (2): 758-762 (2015)" }, { "key": "ref16", "doi": "10.1016/j.phytochem.2006.06.017", "unstructured": "Richa Panday, Madan M. Gupta. Heteroyohimbinoid type oxindole alkaloids fownmitragynaparrifolia, Phytochemistry Vol.67, issue 19 octomber 2006, Page 2164-2169" }, { "key": "ref17", "unstructured": "Sharda Roy, Vikas Chandra Roy, dr. R. C. Roy, A Review of M.P. (Roxb) Korth: PHARMATUTOR–2013" }, { "key": "ref18", "unstructured": "Ankit Saneja1, Dhirender Kaushik1*, Sukhbir Lal Khokra1, Pawan Kaushik, Chetan Sharma and K.R. Aneja Evaluation of activities of M. P. fruit extract: Journal of Natural product. Volume 2, 49-54. (2009)" }, { "key": "ref19", "doi": "10.25004/ijpsdr.2009.010102", "unstructured": "Kaushik D, KhokraS.. L., Kauship P., Sanjena A, Sharma C, Aneja K. R., Chaudhary B, Koshy S., Study of analgesic and antimicrobial Potential of MitragynaParvifoliaIJPSDR Apr-June, 2009, Vol 1, Issue 1(6-8)" }, { "key": "ref20", "unstructured": "Dhirendar Kaushik, SukhbirlalKhokra, Pawan Kaushik, Ankit Saneja, Divya Arora. Anticonvulsant activity of mitragynaparvifolia leaves extract: (Pharmacologyonline 3, 101-106, 2009)" }, { "key": "ref21", "unstructured": "Vishal B. Vadgujar, Sanjay j. Surana. In vitro investigation of anthelmintic activity of P.R.K. : Vishal B. Vadgujar, Sanjay j. Surana, Veternary world 3(7)326, 2010" }, { "key": "ref22", "unstructured": "R. K. Sahu, G. Tatewar, A. Roy and A. K. Jha ANTHEMINTIC ACTIVITY OF MITROGYNA PARVIFOLIA (ROXB) KORTH FRUIT EXTRACT : World Journal of Pharmacy & Pharmaceutical Science 6 (12) 1349-1354, 2017" }, { "key": "ref23", "unstructured": "Vikas Gupta, Pawan Kumar, Parveen Bansal, Ranjeet Singh Antinflammatory and antinociceptive activity of MitragynaParvifolia:" }, { "key": "ref24", "unstructured": "Pundir Ram Kumar, Bishnoi Shreya, Antimicrobial activity of mitragynaparvifolia barks and Butea monosperma leaves extract against human pathogenic microbial strain.: International Journal of Drug Development and research 3(4) 0-0, 2011" }, { "key": "ref25", "unstructured": "Vishal B. B., Sanjay J. S, Anxiolytic Investigation of anxiolytic effect of M.P. stem Bark extracts an animal model: Journal Article–Der Phwamacia letter 2009, Vol. 1 No. 2 P. P. 172-181" }, { "key": "ref26", "unstructured": "Arindam A Ghatak, ND Bhembre, Anisha A Kamath, Sneha S. Mehta, MR Mendonca AW. Antiproliferative, antioxidant activity and total phenolic content of MitragynaparifoliaKorth Int J Parm Sci 6 (4), 632–637, 2014" }, { "key": "ref27", "unstructured": "A. P. Jain, M. V. Tole, A. Mittal, N. B. Mahire, Antiarthritic and antipyretic activity of MitragyanaParvifolia : January 2009, Pharcocalogyonline 2:739–749" }, { "key": "ref28", "unstructured": "Amit Gupta and Sushma R. ChaphalkarImmunosupressive and cytotoxic potential of flavanoids form Mitragynaparvifolia, Magnifera Indica and Argle Marmelosa" }, { "key": "ref29", "unstructured": "Ghosh Rimi, Murali Anita, Gowri R. Evaluation of anti-Hypertensive activity of Mitragynaparvifolia (Rox B) Korth root extract and its vasorelaxation potential on calcium chloride induced contraction in asolated rat Aorta: JOURNAL OF DENTAL AND OROFACIAL RESEARCH 14 (1) pp : 28-34, Published : Jan 2018-2019" }, { "key": "ref30", "doi": "10.30799/jnst.133.18040415", "unstructured": "Shailesh C. Kotval, Tessy John, Kokila A Parmar. Green synthesis of copper nanoparticles using mitragynaparvifolia plant bark extract and it’s a antimicrobial study, Journal of Nanoscience and technology" }, { "key": "ref31", "unstructured": "Anjana Goel, Rashmi Singh, Sandee Kumar Dash, Deepti Gupta. Antiviral activity of few selected indigenous plants against bovine herpes virus-1,Dihydro 16-17, June 2011" }, { "key": "ref32", "doi": "10.1016/j.ejps.2012.07.012", "unstructured": "Ashutosh Shukla et at. b–hydroxyl isomitraphylline alkaloid as an inhibitor of DPP–IV, and its effect on incretin harmone and β–cell proliferation in diabetic rat :Eur Pharm Sci.2012 National Library of medicine. Published by: Longman Publishers www.jst.org.in P a g e 59 | 7" }, { "key": "ref33", "unstructured": "K PashupatVasmatkar, Ashutosh Dubey, Bhawna Tyagi, Pratibha Baral, Shishir Tondon, Amar MS analysis of methanolic extract from stem back & leaves of M.P. (r)" }, { "key": "ref34", "doi": "10.52816/jdvat.2021.1103", "unstructured": "R.Padmavati, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF MITAGYNA PARVIFOLIA LEAF EXTRACTS IN EXPERIMENTAL RATS; Journal of Drug vigilance and alternative therapies, January 2021, DOl : 10.528161/JDVAT 2021.1103" } ], "record": { "registrant": "Longman Publishers", "registered": "2024-02-16", "updated": "2026-09-17", "issue_number": 1, "source": "crossref-api", "source_agency": "Crossref (member 25296)" } }, "url_after": "https://www.jst.org.in/index.php/pub/article/view/591", "sha256_before": "f6738e45e7a05578f6161dc081345f4b2899fae24fbbd75affb5de69f1287bf2", "sha256_after": "b3046fc8e6ba14bd188b4c0292e886318693413a87280dffac96bc91b08a7d79" } ] }